Mice homozygous for null allele die in the early postnatal period of an obstructive arterial disease. They exhibit a decrease in arterial diameter due to subendothelial accumulation of arterial smooth muscle, and display defective terminal airway development resulting in emphysematous morphology.
|Process||extracellular matrix organization, regulation of actin filament polymerization, ...|
|Component||elastic fiber, extracellular region, ...|
|Function||extracellular matrix binding, extracellular matrix structural constituent, ...|
|RNA in situ||281|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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