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Adipor2 Gene Detail
Summary
  • Symbol
    Adipor2
  • Name
    adiponectin receptor 2
  • Synonyms
    1110001I14Rik, D6Ucla1e
  • Feature Type
    protein coding gene
  • IDs
    MGI:93830
    NCBI Gene: 68465
Location & Maps
more
  • Sequence Map
    Chr6:119353150-119417704 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      64555 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    ADIPOR2, adiponectin receptor 2
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ADIPOR2, adiponectin receptor 2
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ACDCR2, PAQR2
  • Links
    NCBI Gene ID: 79602
    neXtProt AC: NX_Q86V24

  • Chr Location
    12p13.31; chr12:1690981-1788679 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    38 phenotypes from 4 alleles in 4 genetic backgrounds
    10 phenotypes from multigenic genotypes
    24 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
Mice homozygous for disruptions in this gene display small testes and epididymis, degeneration of the seminiferous tubules, and abnormal sperm maturation.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049368 VEGA Gene Model | MGI Sequence Detail 64555 C57BL/6J ±  kb
transcript OTTMUST00000125842 VEGA | MGI Sequence Detail 4184 Not Applicable  
polypeptide OTTMUSP00000068113 VEGA | MGI Sequence Detail 386 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    333 from dbSNP Build 137
  • RFLP
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000003779 adiponectin receptor protein 2
  • InterPro Domains
    IPR004254 AdipoR/Haemolysin-III-related
Molecular
Reagents
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  • All nucleic 209
    cDNA 206
    Primer pair 2
    Other 1

    Microarray probesets 5
Other
Accession IDs
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MGD-MRK-7736, MGI:1889386, MGI:1915715, MGI:2141699
References
more
  • Summaries
    All 67
    Developmental Gene Expression 11
    Gene Ontology 6
    Phenotypes 24
  • Earliest
    J:15567 Warden CH, et al., Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse. Genomics. 1993 Nov;18(2):295-307
  • Latest
    J:215944 Parker-Duffen JL, et al., Divergent roles for adiponectin receptor 1 (AdipoR1) and AdipoR2 in mediating revascularization and metabolic dysfunction in vivo. J Biol Chem. 2014 Jun 6;289(23):16200-13

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/26/2016
MGI 6.02
The Jackson Laboratory