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Serpina1d
Gene Detail
Symbol

Name
ID
Serpina1d
serine (or cysteine) peptidase inhibitor, clade A, member 1D
MGI:891968
Synonyms
PI4, Spi1-4
Feature Type
protein coding gene
Genetic Map
Chromosome 12
52.98 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr12:103763594-103773592 bp, - strand
From VEGA annotation of GRCm38

  9999 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20103  Vertebrate Homology Class
1 human; 5 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 4 chicken; 3 western clawed frog; 2 zebrafish

Protein SuperFamily: serpin
Gene Tree: Serpina1d

Human
homologs
Human Homolog SERPINA1, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
NCBI Gene ID 5265
neXtProt AC  NX_P01009
Human Synonyms  A1A, A1AT, AAT, alpha1AT, PI, PI1, PRO2275
Human Chr (Location)  14q32.1; chr14:94376747-94390692 (-)  GRCh38
Disease Associations  (2) Diseases Associated with Human SERPINA1
Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Interactions
Serpina1d interacts with 14 markers (Mir22, Mir218-2, Mir222, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
Data Summary: Results (48)    Tissues (6)    Images (21)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 48
cDNA source data(4)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(6) Genomic(2) cDNA(4)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000027640 (Evidence)
Ensembl Gene ModelENSMUSG00000071177 (Evidence)
Entrez Gene20703 (Evidence)
Consensus CDS ProjectCCDS26139.1
International Mouse Knockout Project StatusSerpina1d
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027640 VEGA Gene Model | MGI Sequence Detail 9999 C57BL/6J ±  kb
transcript OTTMUST00000068385 VEGA | MGI Sequence Detail 1394 Not Applicable 
polypeptide OTTMUSP00000034565 VEGA | MGI Sequence Detail 413 Not Applicable 

For the selected sequences
All sequences(17) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(198 from dbSNP Build 137)    SNPs within 2kb including multiple locations(262)
Protein-related
information
ResourceIDDescription
InterPro IPR023795 Protease inhibitor I4, serpin, conserved site
InterPro IPR023796 Serpin domain
InterPro IPR000215 Serpin family
Protein Ontology PR:000015930 alpha-1-antitrypsin 1-4
References
(Earliest) J:23546 Borriello F, et al., Multiple murine alpha 1-protease inhibitor genes show unusual evolutionary divergence. Proc Natl Acad Sci U S A. 1991 Nov 1;88(21):9417-21
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(26)
Other
accession IDs
MGI:2144762

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory