Serpina1d
Gene Detail

Symbol Name ID

Serpina1d serine (or cysteine) peptidase inhibitor, clade A, member 1D MGI:891968

Synonyms

PI4, Spi1-4

Feature Type

protein coding gene

Genetic Map

Chromosome 12

52.98 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr12:103763594-103773592 bp, - strand From VEGA annotation of GRCm38   9999 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:20103  Vertebrate Homology Class
1 human; 5 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 5 chicken; 2 zebrafish

Protein SuperFamily: serpin
Gene Tree: Serpina1d

Human homologs

Human Homolog		SERPINA1, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
NCBI Gene ID		5265
neXtProt AC		NX_P01009
Human Synonyms		A1A, A1AT, AAT, alpha1AT, PI, PI1, PRO2275
Human Chr (Location)		14q32.1; chr14:94843084-94857029 (-)  GRCh37.p10
Disease Associations		(2) Diseases Associated with Human SERPINA1

Gene Ontology (GO) classifications

All GO classifications: (10 annotations)

Process	negative regulation of endopeptidase activity, regulation of proteolysis, ...
Component	extracellular region, extracellular space
Function	endopeptidase inhibitor activity, protease binding, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (48)    Tissues (6)    Images (21)
Theiler Stages: 23

Assay Type	Results
RNA in situ	48

cDNA source data(4)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(6) Genomic(2) cDNA(4)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000027640 (Evidence)
Ensembl Gene Model	ENSMUSG00000071177 (Evidence)
Entrez Gene	20703 (Evidence)
Consensus CDS Project	CCDS26139.1
International Mouse Knockout Project Status	Serpina1d

Sequences

Length	Strain/Species
genomic	OTTMUSG00000027640	VEGA Gene Model | MGI Sequence Detail	9999	C57BL/6J
transcript	OTTMUST00000068385	VEGA | MGI Sequence Detail	1394	Not Applicable
polypeptide	OTTMUSP00000034565	VEGA | MGI Sequence Detail	413	Not Applicable

All sequences(24) RefSeq(12)

Polymorphisms

SNPs(59 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
Protein Ontology	PR:000015930	alpha-1-antitrypsin 1-4

References

(Earliest) J:23546 Borriello F, et al., Multiple murine alpha 1-protease inhibitor genes show unusual evolutionary divergence. Proc Natl Acad Sci U S A. 1991 Nov 1;88(21):9417-21
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(24)

Other accession IDs

MGI:2144762