Pcdhb Complex/Cluster/Region Detail

Summary

• Symbol
  Pcdhb
• Name
  protocadherin beta cluster

• Feature Type
  complex/cluster/region
• IDs
  MGI:6331285
• Cluster Members
  Pcdhb1, Pcdhb2, Pcdhb3 ... (22 members)

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 18, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotype references
  

• All Mutations and Alleles
  7
• Endonuclease-mediated
  1
• Targeted
  6
• Genomic Mutations
  5 involving Pcdhb
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  43
• Tissues
  12
• cDNA Data
  1
• Literature Summary
  1

Images

Tissue x Stage Matrix

Molecular
Reagents

• All nucleic 24

  cDNA 1

  Primer pair 23

References

• Summaries
  All 10

  Developmental Gene Expression 1

  Phenotypes 5
• Earliest
  J:312046 Hirano K, et al., Single-neuron diversity generated by Protocadherin-beta cluster in mouse central and peripheral nervous systems. Front Mol Neurosci. 2012;5:90
• Latest
  J:332241 Kobayashi H, et al., Isoform requirement of clustered protocadherin for preventing neuronal apoptosis and neonatal lethality. iScience. 2023 Jan 20;26(1):105766

Pcdhb Cluster contains:

More Data for these features

Member	Feature Type	Location
Pcdhb1, protocadherin beta 1	protein coding gene	Chr18:37397991-37400578 (+)
Pcdhb2, protocadherin beta 2	protein coding gene	Chr18:37427893-37430667 (+)
Pcdhb3, protocadherin beta 3	protein coding gene	Chr18:37433852-37437638 (+)
Pcdhb4, protocadherin beta 4	protein coding gene	Chr18:37440508-37444225 (+)
Pcdhb5, protocadherin beta 5	protein coding gene	Chr18:37453434-37456966 (+)
Pcdhb6, protocadherin beta 6	protein coding gene	Chr18:37466913-37470491 (+)
Pcdhb7, protocadherin beta 7	protein coding gene	Chr18:37474755-37478255 (+)
Pcdhb8, protocadherin beta 8	protein coding gene	Chr18:37488324-37490663 (+)
Pcdhb9, protocadherin beta 9	protein coding gene	Chr18:37533908-37536962 (+)
Pcdhb10, protocadherin beta 10	protein coding gene	Chr18:37544727-37547567 (+)
Pcdhb11, protocadherin beta 11	protein coding gene	Chr18:37554471-37558085 (+)
Pcdhb12, protocadherin beta 12	protein coding gene	Chr18:37568674-37571707 (+)
Pcdhb13, protocadherin beta 13	protein coding gene	Chr18:37575570-37579262 (+)
Pcdhb14, protocadherin beta 14	protein coding gene	Chr18:37580710-37584147 (+)
Pcdhb15, protocadherin beta 15	protein coding gene	Chr18:37606599-37609393 (+)
Pcdhb16, protocadherin beta 16	protein coding gene	Chr18:37610867-37616091 (+)
Pcdhb17, protocadherin beta 17	protein coding gene	Chr18:37618040-37621345 (+)
Pcdhb18, protocadherin beta 18	protein coding gene	Chr18:37622524-37627558 (+)
Pcdhb19, protocadherin beta 19	protein coding gene	Chr18:37630049-37637181 (+)
Pcdhb20, protocadherin beta 20	protein coding gene	Chr18:37637332-37640713 (+)
Pcdhb21, protocadherin beta 21	protein coding gene	Chr18:37646678-37650260 (+)
Pcdhb22, protocadherin beta 22	protein coding gene	Chr18:37651402-37657532 (+)