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Pcdhb7 Gene Detail
Summary
  • Symbol
    Pcdhb7
  • Name
    protocadherin beta 7
  • Synonyms
    Pcdhb4B, PcdhbG
  • Feature Type
    protein coding gene
  • IDs
    MGI:2136741
    NCBI Gene: 93878
  • Member of
    Pcdhb cluster
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:37474755-37478255 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 18, 19.47 cM, cytoband B3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    106 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2136741
protein coding gene Chr18:37474755-37478260 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024316
protein coding gene Chr18:35737528-35741468 (+)
A/J MGP_AJ_G0024283
protein coding gene Chr18:34528506-34532005 (+)
AKR/J MGP_AKRJ_G0024251
protein coding gene Chr18:35481585-35486009 (+)
BALB/cJ MGP_BALBcJ_G0024282
protein coding gene Chr18:34557556-34562363 (+)
C3H/HeJ MGP_C3HHeJ_G0024049
protein coding gene Chr18:35542415-35545914 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024724
protein coding gene Chr18:37036299-37039920 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022163
protein coding gene Chr18:34587811-34591285 (+)
CAST/EiJ MGP_CASTEiJ_G0023524
protein coding gene Chr18:35508790-35514618 (+)
CBA/J MGP_CBAJ_G0024018
protein coding gene Chr18:38120280-38125468 (+)
DBA/2J MGP_DBA2J_G0024148
protein coding gene Chr18:34118971-34122470 (+)
FVB/NJ MGP_FVBNJ_G0024115
protein coding gene Chr18:33839545-33843039 (+)
LP/J MGP_LPJ_G0024232
protein coding gene Chr18:35830167-35834755 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024145
protein coding gene Chr18:39389620-39393746 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024773
protein coding gene Chr18:35336508-35340007 (+)
PWK/PhJ MGP_PWKPhJ_G0023269
protein coding gene Chr18:34357173-34360877 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023074
protein coding gene Chr18:35587051-35590550 (+)
WSB/EiJ MGP_WSBEiJ_G0023587
protein coding gene Chr18:35238691-35243538 (+)



Homology
more
  • Human Ortholog
    PCDHB4, protocadherin beta 4
  • Vertebrate Orthologs
    13
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PCDHB4, protocadherin beta 4
  • Synonyms
    PCDH-BETA4
  • Links
    NCBI Gene ID: 56131
    neXtProt AC: NX_Q9Y5E5
    UniProt: Q9Y5E5

  • Chr Location
    5q31.3; chr5:141121818-141125623 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000045062 Ensembl Gene Model | MGI Sequence Detail 3501 C57BL/6J ±  kb
transcript ENSMUST00000053037 Ensembl | MGI Sequence Detail 3501 Not Applicable  
polypeptide ENSMUSP00000051041 Ensembl | MGI Sequence Detail 829 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    cDNA 6
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 25
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:67989 Wu Q, et al., Comparative dna sequence analysis of mouse and human protocadherin gene clusters. Genome Res. 2001 Mar;11(3):389-404
  • Latest
    J:332241 Kobayashi H, et al., Isoform requirement of clustered protocadherin for preventing neuronal apoptosis and neonatal lethality. iScience. 2023 Jan 20;26(1):105766

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory