About   Help   FAQ
Pcdhb1 Gene Detail
Summary
  • Symbol
    Pcdhb1
  • Name
    protocadherin beta 1
  • Synonyms
    PcdhbA
Location &
Maps
more
  • Sequence Map
    Chr18:37397991-37400578 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 19.46 cM, cytoband B3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    170 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2136730
 protein coding gene Chr18:37397897-37400578 (+)
129S1/SvImJ ENSMUSG00200042507
 protein coding gene Chr18:34397399-34399986 (+)
A/J ENSMUSG00195034366
 protein coding gene Chr18:34550397-34552984 (+)
AKR/J ENSMUSG00220016089
 protein coding gene Chr18:34540508-34543095 (+)
BALB/cJ ENSMUSG00180015204
 protein coding gene Chr18:35000023-35002610 (+)
C3H/HeJ ENSMUSG00175033387
 protein coding gene Chr18:34522039-34524626 (+)
C57BL/6NJ ENSMUSG00215018575
 protein coding gene Chr18:34267495-34270082 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022157
 protein coding gene Chr18:34513084-34515671 (+)
CAST/EiJ ENSTCUG00005021009
 protein coding gene Chr18:34147570-34150157 (+)
CBA/J ENSMUSG00210020674
 protein coding gene Chr18:34542041-34544628 (+)
DBA/2J ENSMUSG00185017496
 protein coding gene Chr18:34476680-34479267 (+)
FVB/NJ ENSMUSG00205023206
 protein coding gene Chr18:34202319-34204906 (+)
JF1/MsJ ENSUMUG00000045858
 protein coding gene Chr18:34616926-34619507 (+)
LP/J ENSMUSG00230042961
 protein coding gene Chr18:36594069-36596656 (+)
NOD/ShiLtJ ENSMUSG00190017133
 protein coding gene Chr18:34270351-34272938 (+)
NZO/HlLtJ ENSMUSG00225045477
 protein coding gene Chr18:36492122-36494709 (+)
PWK/PhJ ENSLUMG00010011487
 protein coding gene Chr18:34779654-34782241 (+)
SPRET/EiJ ENSMSPG00010021429
 protein coding gene Chr18:34826743-34829330 (+)
WSB/EiJ ENSIUOG00005007122
 protein coding gene Chr18:34255677-34258264 (+)



Homology
more
  • Human Ortholog
    PCDHB1, protocadherin beta 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PCDHB1, protocadherin beta 1
  • Synonyms
    PCDH-BETA1
  • Links
    NCBI Gene ID: 29930
    UniProt: Q9Y5F3

  • Chr Location
    5q31.3; chr5:141051374-141059346 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    626
  • Tissues
    25
  • cDNA Data
    4
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000051663 Ensembl Gene Model | MGI Sequence Detail 2588 C57BL/6J ±  kb
transcript ENSMUST00000052366 Ensembl | MGI Sequence Detail 2588 Not Applicable  
polypeptide ENSMUSP00000057519 Ensembl | MGI Sequence Detail 818 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • PDB
    4ZPL
  • InterPro Domains
    IPR020894 Cadherin conserved site
    IPR032455 Cadherin, cytoplasmic C-terminal domain
    IPR002126 Cadherin-like
    IPR015919 Cadherin-like superfamily
    IPR013164 Cadherin, N-terminal
    IPR050174 Protocadherin/Cadherin-related Cell Adhesion
  • GlyGen
    Q91Y08 4 sites, 2 N-linked glycans (2 sites)
Molecular
Reagents
less
  • All nucleic 7
    cDNA 4
    Primer pair 3

    Microarray probesets 2
References
more
  • Summaries
    All 27
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:86878 Wu Q, et al., A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell. 1999 Jun 11;97(6):779-90
  • Latest
    J:332241 Kobayashi H, et al., Isoform requirement of clustered protocadherin for preventing neuronal apoptosis and neonatal lethality. iScience. 2023 Jan 20;26(1):105766
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory