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Pcdhb11 Gene Detail
Summary
  • Symbol
    Pcdhb11
  • Name
    protocadherin beta 11
  • Synonyms
    Pcdhb5E, PcdhbK
  • Feature Type
    protein coding gene
  • IDs
    MGI:2136746
    NCBI Gene: 93882
  • Member of
    Pcdhb cluster
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:37554471-37558085 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 19.49 cM, cytoband B3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    72 from dbSNP Build 142
  • Strain Annotations
    13
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2136746
 protein coding gene Chr18:37554471-37558889 (+)
129S1/SvImJ no annotation
A/J MGP_AJ_G0024287
 protein coding gene Chr18:34594010-34598767 (+)
AKR/J MGP_AKRJ_G0024255
 protein coding gene Chr18:35545839-35550695 (+)
BALB/cJ MGP_BALBcJ_G0024286
 protein coding gene Chr18:34640997-34645415 (+)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0024728
 protein coding gene Chr18:37113431-37118307 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022167
 protein coding gene Chr18:34648108-34650835 (+)
CAST/EiJ MGP_CASTEiJ_G0023526
 protein coding gene Chr18:35554548-35559939 (+)
CBA/J MGP_CBAJ_G0024022
 protein coding gene Chr18:38200088-38207895 (+)
DBA/2J MGP_DBA2J_G0024152
 protein coding gene Chr18:34191193-34195611 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0024236
 protein coding gene Chr18:35897402-35901820 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024149
 protein coding gene Chr18:39474205-39479421 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024777
 protein coding gene Chr18:35413271-35417689 (+)
PWK/PhJ MGP_PWKPhJ_G0023266
 protein coding gene Chr18:34321877-34432149 (+)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    PCDHB5, protocadherin beta 5
  • Vertebrate Orthologs
    7
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PCDHB5, protocadherin beta 5
  • Synonyms
    PCDH-BETA5
  • Links
    NCBI Gene ID: 26167
    neXtProt AC: NX_Q9Y5E4
    UniProt: Q9Y5E4

  • Chr Location
    5q31.3; chr5:141135206-141138615 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    732
  • Tissues
    24
  • cDNA Data
    9
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 93882 NCBI Gene Model | MGI Sequence Detail 3615 C57BL/6J ±  kb
transcript NM_053136 RefSeq | MGI Sequence Detail 3615 C57BL/6  
polypeptide NP_444366 RefSeq | MGI Sequence Detail 797 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 9
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 26
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:67989 Wu Q, et al., Comparative dna sequence analysis of mouse and human protocadherin gene clusters. Genome Res. 2001 Mar;11(3):389-404
  • Latest
    J:332241 Kobayashi H, et al., Isoform requirement of clustered protocadherin for preventing neuronal apoptosis and neonatal lethality. iScience. 2023 Jan 20;26(1):105766
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory