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Slc22a28 Gene Detail
Summary
  • Symbol
    Slc22a28
  • Name
    solute carrier family 22, member 28
  • Synonyms
    Gm5631
  • Feature Type
    protein coding gene
  • IDs
    MGI:3645714
    NCBI Gene: 434674
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr19:8062209-8131982 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 5.39 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    372 from dbSNP Build 142
  • Strain Annotations
    6
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3645714
protein coding gene Chr19:8062209-8131982 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J MGP_AKRJ_G0024741
protein coding gene Chr19:4780541-5434245 (-)
BALB/cJ MGP_BALBcJ_G0024767
protein coding gene Chr19:4998585-5125470 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0025213
protein coding gene Chr19:5355835-5460899 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0024601
protein coding gene Chr19:5207549-5274673 (-)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0025261
protein coding gene Chr19:4948318-5464708 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    SLC22A25, solute carrier family 22 member 25
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SLC22A25, solute carrier family 22 member 25
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HIMTP, UST6
  • Links
    NCBI Gene ID: 387601
    neXtProt AC: NX_Q6T423
    UniProt: Q6T423

  • Chr Location
    11q12.3; chr11:63162264-63243523 (-)  GRCh38.p7

  • Human Ortholog
    SLC22A9, solute carrier family 22 member 9
    Orthology source: HGNC
  • Synonyms
    HOAT4, OAT4, OAT7, ust3, UST3H
  • Links
    NCBI Gene ID: 114571
    neXtProt AC: NX_Q8IVM8
    UniProt: Q8IVM8

  • Chr Location
    11q12.3; chr11:63368871-63410878 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000063590 Ensembl Gene Model | MGI Sequence Detail 69774 C57BL/6J ±  kb
transcript ENSMUST00000065651 Ensembl | MGI Sequence Detail 2004 Not Applicable  
polypeptide ENSMUSP00000067114 Ensembl | MGI Sequence Detail 552 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR005828 Major facilitator, sugar transporter-like
    IPR020846 Major facilitator superfamily domain
    IPR036259 MFS transporter superfamily
Molecular
Reagents
less
  • All nucleic 12
    cDNA 11
    Primer pair 1
References
more
  • Summaries
    All 13
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 2
  • Earliest
    J:157965 Wu W, et al., Analysis of a large cluster of SLC22 transporter genes, including novel USTs, reveals species-specific amplification of subsets of family members. Physiol Genomics. 2009 Jul 9;38(2):116-24
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory