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Wdr81
Gene Detail
Symbol

Name
ID
Wdr81
WD repeat domain 81
MGI:2681828
Synonyms
MGC32441, MGC:32441
Feature Type
protein coding gene
Genetic Map
Chromosome 11
45.89 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:75440948-75454438 bp, - strand
From VEGA annotation of GRCm38

  13491 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:13983  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: WDR81
Gene Tree: Wdr81

Human
homologs
WDR81, WD repeat domain 81
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 124997
neXtProt AC: NX_Q562E7

Human Synonyms: CAMRQ2, PPP1R166

Human Chr (Location): 17p13.3; chr17:1716523-1738599 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human WDR81

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(4) Targeted(1)
Genomic Mutations involving Wdr81 (1)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Wdr81 interacts with 139 markers (Mir15a, Mir17, Mir18, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process negative regulation of phosphatase activity
Component cellular_component
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(54)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase wdr81    NEW 
Molecular
reagents
All nucleic(54) cDNA(54)
Microarray probesets(2)
Other database
links
VEGA Gene Model OTTMUSG00000006200 (Evidence)
Ensembl Gene Model ENSMUSG00000045374 (Evidence)
Entrez Gene 192652 (Evidence)
UniGene 340378
DFCI TC1601280, TC1610367, TC1689433
DoTS DT.101702898, DT.55174242, DT.40155049, DT.110539320
NIA Mouse Gene Index U033079
Consensus CDS Project CCDS48849.1
International Mouse Phenotyping Consortium Status Wdr81
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006200 VEGA Gene Model | MGI Sequence Detail 13491 C57BL/6J ±  kb
transcript OTTMUST00000013981 VEGA | MGI Sequence Detail 6625 Not Applicable 
polypeptide OTTMUSP00000006494 VEGA | MGI Sequence Detail 1934 Not Applicable 

For the selected sequences
All sequences(61) RefSeq(14) UniProt(7)
Polymorphisms
SNPs within 2kb(80 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000409 BEACH domain
InterPro IPR011009 Protein kinase-like domain
InterPro IPR001680 WD40 repeat
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000031243 WD repeat-containing protein 81
References
(Earliest) J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(27)
Other
accession IDs
MGI:2685729

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory