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Wdr81 Gene Detail
Summary
  • Symbol
    Wdr81
  • Name
    WD repeat domain 81
  • Synonyms
    MGC32441, MGC:32441
  • Feature Type
    protein coding gene
  • IDs
    MGI:2681828
    NCBI Gene: 192652
Location & Maps
more
  • Sequence Map
    Chr11:75440948-75454438 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      13491 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    WDR81, WD repeat domain 81
  • Vertebrate Orthologs
    9
  • Human Ortholog
    WDR81, WD repeat domain 81
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CAMRQ2, PPP1R166, SORF-2
  • Links
    NCBI Gene ID: 124997
    neXtProt AC: NX_Q562E7

  • Chr Location
    17p13.3; chr17:1716523-1738599 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human WDR81 associations

Human Disease Mouse Models
       Cerebellar Ataxia, Mental Retardation, and Dysequilibrium Syndrome 2; CAMRQ2   OMIM: 610185
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    4
  • Targeted
    1
  • Genomic Mutations
    2 involving Wdr81
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006200 VEGA Gene Model | MGI Sequence Detail 13491 C57BL/6J ±  kb
transcript OTTMUST00000013981 VEGA | MGI Sequence Detail 6625 Not Applicable  
polypeptide OTTMUSP00000006494 VEGA | MGI Sequence Detail 1934 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    80 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 54
    cDNA 54

    Microarray probesets 2
Other
Accession IDs
less
MGI:2685729
References
more
  • Summaries
    All 25
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory