Wdr81 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Wdr81
WD repeat domain 81
MGI:2681828

18 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Wdr81^em1(IMPC)J/Wdr81⁺ C57BL/6NJ-Wdr81^em1(IMPC)J/J	decreased grip strength	J:211773
Wdr81^em1(IMPC)J/Wdr81⁺ C57BL/6NJ-Wdr81^em1(IMPC)J/J	increased blood urea nitrogen level	J:211773
Wdr81^em1(IMPC)J/Wdr81^em1(IMPC)J C57BL/6NJ-Wdr81^em1(IMPC)J/J	preweaning lethality, complete penetrance	J:211773
Wdr81^m1Btlr/Wdr81^m1Btlr C57BL/6J-Wdr81^m1Btlr	ataxia	J:267697
Wdr81^m1Btlr/Wdr81^m1Btlr C57BL/6J-Wdr81^m1Btlr	decreased body weight	J:267697
Wdr81^nur5/Wdr81^nur5 involves: C57BL/6J	abnormal gait	J:196651
	abnormal neuron mitochondrial morphology	J:196651
	abnormal Purkinje cell dendrite morphology	J:196651
	ataxia	J:196651
	decreased cerebellar granule cell number	J:196651
	decreased Purkinje cell number	J:196651
	decreased retina photoreceptor cell number	J:196651
	decreased total retina thickness	J:196651
	disorganized mitochondrial cristae	J:196651
	impaired coordination	J:196651
	increased mitochondrial size	J:196651
	short stride length	J:196651
	tremors	J:85113, J:196651
	weight loss	J:196651

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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