hydrocephalus Disease Ontology Browser

Disease Ontology Browser

hydrocephalus (DOID:10908)
Alliance: disease page
Synonyms: hydrocephalus, nonsyndromic, autosomal recessive; hydrocephalus, X-linked
Alt IDs: OMIM:123155, OMIM:236600, OMIM:236635, OMIM:307000, OMIM:615219, ICD10CM:G91, MESH:D006849, NCI:C3111, ORDO:2182, ORDO:2185, UMLS_CUI:C0020255
Definition: A cerebral degeneration characterized by an abnormal accumulation of cerebrospinal fluid in the ventricles of the brain, leading to progressive enlargement of the head.

Term Browser
Genes (25)
Models (21)

Disease References using Mouse Models (10)

Mouse Models

Human Disease Modeled: hydrocephalus
Associated Mouse Gene: Add1

Allelic Composition	Genetic Background	Reference	Phenotypes
Add1tm1Llp/Add1tm1Llp	involves: 129P2/OlaHsd * 129S1/SvImJ * C57BL/6J	J:138919	View

Mouse Models

Human Disease Modeled: hydrocephalus
Associated Mouse Gene: Ak7

Allelic Composition	Genetic Background	Reference	Phenotypes
Ak7Gt(OST434404)Lex/Ak7Gt(OST434404)Lex	involves: 129S5/SvEvBrd * C57BL/6J	J:185566	View

Mouse Models

Human Disease Modeled: hydrocephalus
Associated Mouse Gene: Ak8

Allelic Composition	Genetic Background	Reference	Phenotypes
Ak8Gt(OST16378)Lex/Ak8Gt(OST16378)Lex	involves: 129S5/SvEvBrd * C57BL/6J	J:185566	View

Mouse Models

Human Disease Modeled: hydrocephalus
Associated Mouse Gene: Ccdc39

Allelic Composition	Genetic Background	Reference	Phenotypes
Ccdc39prh/Ccdc39prh	involves: A/J * FVB/N	J:253968	View

Mouse Models

Human Disease Modeled: hydrocephalus
Associated Mouse Gene: Ccdc85c

Allelic Composition	Genetic Background	Reference	Phenotypes
Ccdc85chhy/Ccdc85chhy	involves: BALB/cHeA * STS/A	J:93608	View

Mouse Models

Human Disease Modeled: hydrocephalus
Associated Mouse Gene: Celsr2

Allelic Composition	Genetic Background	Reference	Phenotypes
Celsr2tm1Lex/Celsr2tm1Lex	involves: 129S5/SvEvBrd * C57BL/6J	J:185566	View

Mouse Models

Human Disease Modeled: hydrocephalus
Associated Mouse Gene: Dpcd

Allelic Composition	Genetic Background	Reference	Phenotypes
Dpcd/PollGt(OST280355)Lex/Dpcd/PollGt(OST280355)Lex	involves: 129S5/SvEvBrd * C57BL/6Brd	J:185566	View

Mouse Models

Human Disease Modeled: hydrocephalus
Associated Mouse Gene: E2f5

Allelic Composition	Genetic Background	Reference	Phenotypes
E2f5tm1Dli/E2f5tm1Dli	either: (involves: 129S1/Sv * BALB/c) or (involves: 129S1/Sv * C57BL/6)	J:47283	View

Mouse Models

Human Disease Modeled: hydrocephalus
Associated Mouse Gene: Hydin

Allelic Composition	Genetic Background	Reference	Phenotypes
Hydinhy3/Hydinhy3	involves: CBA	J:5426	View

Mouse Models

Human Disease Modeled: hydrocephalus
Associated Mouse Gene: Kif27

Allelic Composition	Genetic Background	Reference	Phenotypes
Kif27Gt(OST441915)Lex/Kif27Gt(OST441915)Lex	involves: 129S5/SvEvBrd * C57BL/6J	J:185566	View

Mouse Models

Human Disease Modeled: hydrocephalus
Associated Mouse Gene: Mboat7

Allelic Composition	Genetic Background	Reference	Phenotypes
Mboat7tm1Lex/Mboat7tm1Lex	involves: 129S5/SvEvBrd * C57BL/6J	J:185566	View

Mouse Models

Human Disease Modeled: hydrocephalus
Associated Mouse Gene: Nme5

Allelic Composition	Genetic Background	Reference	Phenotypes
Nme5tm1Lex/Nme5tm1Lex	involves: 129S5/SvEvBrd * C57BL/6J	J:185566	View

Mouse Models

Human Disease Modeled: hydrocephalus
Associated Mouse Gene: Nme7

Allelic Composition	Genetic Background	Reference	Phenotypes
Nme7Gt(OST31116)Lex/Nme7Gt(OST31116)Lex	involves: 129S5/SvEvBrd * C57BL/6Brd	J:185566	View

Mouse Models

Human Disease Modeled: hydrocephalus
Associated Mouse Gene: Pomk

Allelic Composition	Genetic Background	Reference	Phenotypes
PomkGt(OST243203)Lex/PomkGt(OST243203)Lex	involves: 129S5/SvEvBrd * C57BL/6J	J:185566	View

Mouse Models

Human Disease Modeled: hydrocephalus
Associated Mouse Gene: Sox3

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Sox3)1Pqt/0 Tg(Sox3-EGFP)NrPqt/0	involves: C57BL/6 * CBA	J:184232	View

Mouse Models

Human Disease Modeled: hydrocephalus
Associated Mouse Gene: Stk36

Allelic Composition	Genetic Background	Reference	Phenotypes
Stk36tm1Lex/Stk36tm1Lex	involves: 129S5/SvEvBrd * C57BL/6J	J:185566	View

Mouse Models

Human Disease Modeled: hydrocephalus
Associated Mouse Gene: Ulk4

Allelic Composition	Genetic Background	Reference	Phenotypes
Ulk4tm1Lex/Ulk4tm1Lex	involves: 129S5/SvEvBrd * C57BL/6J	J:185566	View

Mouse Models

Human Disease Modeled: hydrocephalus
Associated Mouse Transgene: Tg(Sox3)1Pqt

Allelic Composition	Genetic Background	Reference	Phenotypes
Tg(Sox3)1Pqt/0 Tg(Sox3-EGFP)NrPqt/0	involves: C57BL/6 * CBA	J:184232	View

Mouse Models

Human Disease Modeled: hydrocephalus

Allelic Composition	Genetic Background	Reference	Phenotypes
Fzd3tm1(FZD3)Lex/Fzd3tm1(FZD3)Lex	involves: 129S5/SvEvBrd * C57BL/6J	J:185566	View

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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