Phenotypes Associated with This Genotype

Genotype
MGI:5429555

• Allelic Composition: Ak8^{Gt(OST16378)Lex}/Ak8^{Gt(OST16378)Lex}
• Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:185566 )

N • no notable behavior phenotype despite hydrocephalus

craniofacial

craniofacial phenotype ( J:185566 )

N • doming of head not observed

growth/size/body

growth/size/body region phenotype ( J:185566 )

N • situs inversus was not observed

nervous system

hydrocephaly ( J:185566 )

• mild to moderate hydrocephalus that becomes evident at approximately 2 weeks of age (late onset) and reaches maximum severity by 3 weeks of age

dilated lateral ventricle ( J:185566 )

• mild bilateral dilation of lateral ventricles

small hippocampus ( J:185566 )

• reduced size of hippocampus

reproductive system

reproductive system phenotype ( J:185566 )

N • normal fertility

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
hydrocephalus		DOID:10908	OMIM:123155 OMIM:236600 OMIM:236635 OMIM:307000 OMIM:615219	J:185566