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Klhl3
Gene Detail
 Symbol
Name
ID
Klhl3
kelch-like 3
MGI:2445185
Synonyms 7530408C15Rik, EG627648
Feature Type protein coding gene
Genetic Map
Chromosome 13
30.92 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr13:58004221-58113592 bp, - strand
From VEGA annotation of GRCm38

  109372 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:79542  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: kelch-like protein, gigaxonin type
Gene Tree: Klhl3

Human
homologs
Human Homolog KLHL3, kelch-like family member 3
NCBI Gene ID 26249
neXtProt AC  NX_Q9UH77
Human Synonyms  PHA2D
Human Chr (Location)  5q31; chr5:137617500-137736090 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human KLHL3
Alleles
and
phenotypes
All alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process distal tubule morphogenesis, ion homeostasis, ...
Component Cul3-RING ubiquitin ligase complex, cytoplasm, ...
Function actin binding, catalytic activity
External Resources: FuncBase
Expression
cDNA source data(8)
External Resources: GEO   ArrayExpress
Molecular
reagents
All nucleic(8) cDNA(8)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000034604 (Evidence)
Ensembl Gene ModelENSMUSG00000014164 (Evidence)
Entrez Gene100503085 (Evidence)
DFCITC1598954, TC1632947
DoTSDT.101271891, DT.101355596, DT.101362010
NIA Mouse Gene IndexU034838, U034839
Consensus CDS ProjectCCDS56886.1
International Mouse Knockout Project StatusKlhl3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034604 VEGA Gene Model | MGI Sequence Detail 109372 C57BL/6J ±  kb
transcript OTTMUST00000087800 VEGA | MGI Sequence Detail 3156 Not Applicable 
polypeptide OTTMUSP00000047810 VEGA | MGI Sequence Detail 601 Not Applicable 

For the selected sequences
All sequences(41) RefSeq(16) UniProt(2)
Polymorphisms SNPs within 2kb(1076 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011705 BTB/Kelch-associated
InterPro IPR013069 BTB/POZ
InterPro IPR011333 BTB/POZ fold
InterPro IPR000210 BTB/POZ-like
InterPro IPR015916 Galactose oxidase, beta-propeller
InterPro IPR017096 Kelch-like protein, gigaxonin
InterPro IPR006652 Kelch repeat type 1
InterPro IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase
Protein Ontology PR:000009391 kelch-like protein 3
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(30)
Other
accession IDs
MGI:2145235, MGI:3711978

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory