Phenotypes Associated with This Genotype

Genotype
MGI:5646380

• Allelic Composition: Klhl3^tm1.1Esoh/Klhl3⁺
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

salt-sensitive hypertension ( J:214330 )

• significantly greater increase in systolic blood pressure on a high salt diet

• blood pressure on a normal salt diet is similar to controls

homeostasis/metabolism

hyperkalemia ( J:214330 )

metabolic acidosis ( J:214330 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
pseudohypoaldosteronism		DOID:4479		J:214330