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Nwd1 Gene Detail
Summary
  • Symbol
    Nwd1
  • Name
    NACHT and WD repeat domain containing 1
  • Synonyms
    A230063L24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442268
    NCBI Gene: 319555
  • Gene Overview
    MyGene.info: NWD1
Location & Maps
more
  • Sequence Map
    Chr8:72646711-72717876 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      71166 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 35.08 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    NWD1, NACHT and WD repeat domain containing 1
  • Vertebrate Orthologs
    9
  • Human Ortholog
    NWD1, NACHT and WD repeat domain containing 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 284434
    neXtProt AC: NX_Q149M9

  • Chr Location
    19p13.11; chr19:16719853-16817963 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 72261
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: NWD1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Genomic Mutations
    1 involving Nwd1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000034303 VEGA Gene Model | MGI Sequence Detail 71166 C57BL/6J ±  kb
transcript OTTMUST00000087236 VEGA | MGI Sequence Detail 10792 Not Applicable  
polypeptide OTTMUSP00000047324 VEGA | MGI Sequence Detail 1521 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    344 from dbSNP Build 142
Protein
Information
less
  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000030916 NACHT domain- and WD repeat-containing protein 1
  • InterPro Domains
    IPR024977 Anaphase-promoting complex subunit 4, WD40 domain
    IPR020472 G-protein beta WD-40 repeat
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily
    IPR001680 WD40 repeat
    IPR019775 WD40 repeat, conserved site
    IPR017986 WD40-repeat-containing domain
    IPR015943 WD40/YVTN repeat-like-containing domain
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6
References
more
  • Summaries
    All 16
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory