Nwd1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nwd1
NACHT and WD repeat domain containing 1
MGI:2442268

14 phenotypes from 1 allele in 1 genetic background

Allelic Composition Genetic Background	Annotated Term	Reference
Nwd1^em2.1Sisa/Nwd1^em2.1Sisa involves: C57BL/6 * C57BL/6N * DBA/2	abnormal hepatocyte morphology	J:363603
	abnormal Kupffer cell morphology	J:363603
	abnormal liver physiology	J:363603
	abnormal pulmonary alveolus morphology	J:363603
	enlarged liver	J:363603
	hepatic steatosis	J:363603
	increased endoplasmic reticulum stress	J:363603
	increased leukocyte cell number	J:363603
	increased liver cholesterol level	J:363603
	increased liver triglyceride level	J:363603
	increased pyroptosis	J:363603
	increased susceptibility to xenobiotic induced morbidity/mortality	J:363603
	liver fibrosis	J:363603
	prenatal lethality, incomplete penetrance	J:363603

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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