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Gprasp2 Gene Detail
Summary
  • Symbol
    Gprasp2
  • Name
    G protein-coupled receptor associated sorting protein 2
  • Synonyms
    5330440H13Rik, GASP2, Prpl5
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442071
    NCBI Gene: 245607
  • Gene Overview
    MyGene.info: GPRASP2
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:135839034-135844730 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 57.30 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    39 from dbSNP Build 142
  • Strain Annotations
    12
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442071
protein coding gene ChrX:135839034-135844730 (.)
129S1/SvImJ no annotation
A/J MGP_AJ_G0036069
protein coding gene ChrX:132532188-132583976 (+)
AKR/J MGP_AKRJ_G0035995
protein coding gene ChrX:136789479-136843638 (+)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0035769
protein coding gene ChrX:133165840-133175995 (+)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0033410
protein coding gene ChrX:124614307-124619218 (+)
CAST/EiJ MGP_CASTEiJ_G0035056
protein coding gene ChrX:114049385-114099619 (+)
CBA/J MGP_CBAJ_G0035743
protein coding gene ChrX:141213474-141223484 (+)
DBA/2J MGP_DBA2J_G0035899
protein coding gene ChrX:131875941-131933143 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0035992
protein coding gene ChrX:134108520-134113276 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0036617
protein coding gene ChrX:132534660-132540356 (+)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0034579
protein coding gene ChrX:114725899-114733753 (+)
WSB/EiJ MGP_WSBEiJ_G0035189
protein coding gene ChrX:130873026-130878430 (+)



Homology
more
  • Human Ortholog
    GPRASP2, G protein-coupled receptor associated sorting protein 2
  • Vertebrate Orthologs
    5
  • Human Ortholog
    GPRASP2, G protein-coupled receptor associated sorting protein 2
    Orthology source: HGNC
  • Synonyms
    GASP2
  • Links
    NCBI Gene ID: 114928
    neXtProt AC: NX_Q96D09
    UniProt: Q96D09

  • Chr Location
    Xq22.1; chrX:102712176-102717733 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 245607 NCBI Gene Model | MGI Sequence Detail 5697 C57BL/6J ±  kb
transcript NM_001163015 RefSeq | MGI Sequence Detail 3814 C57BL/6  
polypeptide Q8BUY8 UniProt | EBI | MGI Sequence Detail 826 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 47
    cDNA 47

    Microarray probesets 3
Other
Accession IDs
less
MGI:892978
References
more
  • Summaries
    All 29
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:39869 Yehiely F, et al., Identification of candidate proteins binding to prion protein. Neurobiol Dis. 1997;3(4):339-55
  • Latest
    J:244372 Jung B, et al., Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation. PLoS One. 2016;11(2):e0149477

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory