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Gpr75 Gene Detail
Summary
  • Symbol
    Gpr75
  • Name
    G protein-coupled receptor 75
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441843
    NCBI Gene: 237716
  • Gene Overview
    MyGene.info: GPR75
Location & Maps
more
  • Sequence Map
    Chr11:30885358-30893729 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      8372 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 18.16 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    GPR75, G protein-coupled receptor 75
  • Vertebrate Orthologs
    10
  • Human Ortholog
    GPR75, G protein-coupled receptor 75
    Orthology source: HomoloGene
  • Synonyms
    GPRchr2, WI31133
  • Links
    NCBI Gene ID: 10936
    neXtProt AC: NX_O95800

  • Chr Location
    2p16; chr2:53852913-53860033 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Gpr75
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005353 VEGA Gene Model | MGI Sequence Detail 8372 C57BL/6J ±  kb
transcript OTTMUST00000011940 VEGA | MGI Sequence Detail 2926 Not Applicable  
polypeptide OTTMUSP00000005526 VEGA | MGI Sequence Detail 540 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    114 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000001537 G-protein coupled receptor 75
  • InterPro Domains
    IPR017452 GPCR, rhodopsin-like, 7TM
    IPR000276 G protein-coupled receptor, rhodopsin-like
Molecular
Reagents
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  • All nucleic 6
    cDNA 4
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:213086 Liu B, et al., The novel chemokine receptor, G-protein-coupled receptor 75, is expressed by islets and is coupled to stimulation of insulin secretion and improved glucose homeostasis. Diabetologia. 2013 Nov;56(11):2467-76

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory