About   Help   FAQ
Card14
Gene Detail
Symbol

Name
ID
Card14
caspase recruitment domain family, member 14
MGI:2386258
Synonyms
Bimp2, CARMA2
Feature Type
protein coding gene
Genetic Map
Chromosome 11
83.36 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:119307768-119345375 bp, + strand
From VEGA annotation of GRCm38

  37608 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11469  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Gene Tree: Card14

Human
homologs
Human Homolog CARD14, caspase recruitment domain family, member 14
NCBI Gene ID 79092
neXtProt AC  NX_Q9BXL6
Human Synonyms  BIMP2, CARMA2, PRP, PSORS2, PSS1
Human Chr (Location)  17q25; chr17:80169992-80209331 (+)  GRCh38
Disease Associations  (2) Diseases Associated with Human CARD14
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Card14 interacts with 89 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (8 annotations)
Process apoptotic process, negative regulation of apoptotic process, ...
Component cytoplasm
Function CARD domain binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (30)    Tissues (6)    Images (15)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 30
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(9) cDNA(9)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000003913 (Evidence)
Ensembl Gene ModelENSMUSG00000013483 (Evidence)
Entrez Gene170720 (Evidence)
UniGene130832
DFCITC1588885
NIA Mouse Gene IndexU013631
Consensus CDS ProjectCCDS25715.1
International Mouse Knockout Project StatusCard14
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003913 VEGA Gene Model | MGI Sequence Detail 37608 C57BL/6J ±  kb
transcript OTTMUST00000008678 VEGA | MGI Sequence Detail 4206 Not Applicable 
polypeptide OTTMUSP00000004224 VEGA | MGI Sequence Detail 999 Not Applicable 

For the selected sequences
All sequences(53) RefSeq(30) UniProt(3)
Polymorphisms
SNPs within 2kb(167 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001315 Caspase Recruitment
InterPro IPR011029 Death-like domain
InterPro IPR008144 Guanylate kinase
InterPro IPR001478 PDZ domain
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
Protein Ontology PR:000005035 caspase recruitment domain-containing protein 14
References
(Earliest) J:71748 McAllister-Lucas LM, et al., Bimp1, a MAGUK family member linking protein kinase C activation to Bcl10-mediated NF-kappaB induction. J Biol Chem. 2001 Aug 17;276(33):30589-97
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(26)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/16/2014
MGI 5.20
The Jackson Laboratory