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Card14 Gene Detail
Summary
  • Symbol
    Card14
  • Name
    caspase recruitment domain family, member 14
  • Synonyms
    Bimp2, CARMA2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2386258
    NCBI Gene: 170720
  • Gene Overview
    MyGene.info: CARD14
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:119307768-119345375 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 83.36 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    167 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2386258
protein coding gene Chr11:119307096-119345375 (.)
129S1/SvImJ MGP_129S1SvImJ_G0019479
protein coding gene Chr11:123687501-123728489 (+)
A/J MGP_AJ_G0019447
protein coding gene Chr11:118210092-118245358 (+)
AKR/J MGP_AKRJ_G0019417
protein coding gene Chr11:121768332-121804085 (+)
BALB/cJ MGP_BALBcJ_G0019422
protein coding gene Chr11:118567991-118601696 (+)
C3H/HeJ MGP_C3HHeJ_G0019228
protein coding gene Chr11:122084075-122119163 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019871
protein coding gene Chr11:127459958-127500353 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017496
protein coding gene Chr11:115203137-115240369 (+)
CAST/EiJ MGP_CASTEiJ_G0018782
protein coding gene Chr11:123542407-123589251 (+)
CBA/J MGP_CBAJ_G0019199
protein coding gene Chr11:132415105-132454110 (+)
DBA/2J MGP_DBA2J_G0019311
protein coding gene Chr11:117582444-117615794 (+)
FVB/NJ MGP_FVBNJ_G0019303
protein coding gene Chr11:117249082-117287949 (+)
LP/J MGP_LPJ_G0019383
protein coding gene Chr11:123998008-124049880 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019336
protein coding gene Chr11:131345485-131385893 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019910
protein coding gene Chr11:122442180-122484908 (+)
PWK/PhJ MGP_PWKPhJ_G0018548
protein coding gene Chr11:118988158-119024598 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018340
protein coding gene Chr11:122197654-122240607 (+)
WSB/EiJ MGP_WSBEiJ_G0018834
protein coding gene Chr11:122416469-122467249 (+)



Homology
more
  • Human Ortholog
    CARD14, caspase recruitment domain family member 14
  • Vertebrate Orthologs
    9
  • Human Ortholog
    CARD14, caspase recruitment domain family member 14
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BIMP2, CARMA2, PRP, PSORS2, PSS1
  • Links
    NCBI Gene ID: 79092
    neXtProt AC: NX_Q9BXL6
    UniProt: Q9BXL6

  • Chr Location
    17q25.3; chr17:80169992-80209331 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    2 with human CARD14 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000013483 Ensembl Gene Model | MGI Sequence Detail 37608 C57BL/6J ±  kb
transcript ENSMUST00000106250 Ensembl | MGI Sequence Detail 4206 Not Applicable  
polypeptide ENSMUSP00000101857 Ensembl | MGI Sequence Detail 999 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 2
References
more
  • Summaries
    All 26
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 5
  • Earliest
    J:71748 McAllister-Lucas LM, et al., Bimp1, a MAGUK family member linking protein kinase C activation to Bcl10-mediated NF-kappaB induction. J Biol Chem. 2001 Aug 17;276(33):30589-97
  • Latest
    J:266330 Van Nuffel E, et al., Psoriasis Plays a Wild CARD. J Invest Dermatol. 2018 Sep;138(9):1903-1905

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory