Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable CARD domain binding activity. Predicted to be involved in negative regulation of apoptotic process; positive regulation of protein phosphorylation; and tumor necrosis factor-mediated signaling pathway. Predicted to act upstream of or within apoptotic process. Predicted to be located in aggresome and cytosol. Predicted to be active in cytoplasm. Is expressed in gut; nose; and vibrissa. Used to study psoriasis 2. Human ortholog(s) of this gene implicated in pityriasis rubra pilaris and psoriasis 2. Orthologous to human CARD14 (caspase recruitment domain family member 14).