Symbol
Name
ID

Card14
caspase recruitment domain family, member 14
MGI:2386258

Phenotype annotations related to integument

Darker colors indicate more annotations

Human Phenotypes	Palmoplantar keratoderma	Psoriasiform dermatitis	Subungual hyperkeratosis	Epidermal acanthosis	Scaling skin	Keratosis pilaris	Erythematous plaque	Hypergranulosis	Hyperkeratosis	Orthokeratosis	Parakeratosis
Disease(s) Associated with CARD14	Palmoplantar keratoderma	Psoriasiform dermatitis	Subungual hyperkeratosis	Epidermal acanthosis	Scaling skin	Keratosis pilaris	Erythematous plaque	Hypergranulosis	Hyperkeratosis	Orthokeratosis	Parakeratosis
pityriasis rubra pilaris
psoriasis 2

Mouse Phenotypes

increased keratinocyte proliferation

skin inflammation

decreased susceptibility to chemically induced skin inflammation

abnormal epidermal layer morphology

hyperkeratosis

orthokeratosis

parakeratosis

acanthosis

thick epidermis

dry skin

flaky skin

skin lesions

skin hyperplasia

psoriasis

Availability

Mouse Genotype

Card14^em1Tshu/Card14^em1Tshu

Card14^em9Lutzy/Card14^em9Lutzy

Card14^tm1Lex/Card14^tm1Lex

Card14^em2Tshu/Card14⁺

Card14^em3Tshu/Card14⁺

Card14^em9Lutzy/Card14⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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