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Rin1 Gene Detail
Summary
  • Symbol
    Rin1
  • Name
    Ras and Rab interactor 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385695
    NCBI Gene: 225870
  • Gene Overview
    MyGene.info: RIN1
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:5050481-5057071 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 4.23 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    50 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385695
protein coding gene Chr19:5050019-5057072 (.)
129S1/SvImJ MGP_129S1SvImJ_G0024688
protein coding gene Chr19:1976907-1983182 (+)
A/J MGP_AJ_G0024654
protein coding gene Chr19:1869526-1875798 (+)
AKR/J MGP_AKRJ_G0024627
protein coding gene Chr19:1924580-1930850 (+)
BALB/cJ MGP_BALBcJ_G0024654
protein coding gene Chr19:1865790-1872060 (+)
C3H/HeJ MGP_C3HHeJ_G0024422
protein coding gene Chr19:1927245-1933516 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025101
protein coding gene Chr19:2033972-2040246 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022531
protein coding gene Chr19:1805407-1811351 (+)
CAST/EiJ MGP_CASTEiJ_G0023894
protein coding gene Chr19:1952640-1958911 (+)
CBA/J MGP_CBAJ_G0024393
protein coding gene Chr19:2114746-2121016 (+)
DBA/2J MGP_DBA2J_G0024521
protein coding gene Chr19:1859864-1866134 (+)
FVB/NJ MGP_FVBNJ_G0024488
protein coding gene Chr19:1860945-1867216 (+)
LP/J MGP_LPJ_G0024607
protein coding gene Chr19:1969865-1976138 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024518
protein coding gene Chr19:1997689-2003960 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025149
protein coding gene Chr19:1927157-1933431 (+)
PWK/PhJ MGP_PWKPhJ_G0023640
protein coding gene Chr19:1896350-1902784 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023445
protein coding gene Chr19:1913708-1920101 (+)
WSB/EiJ MGP_WSBEiJ_G0023956
protein coding gene Chr19:1930518-1938322 (+)



Homology
more
  • Human Ortholog
    RIN1, Ras and Rab interactor 1
  • Vertebrate Orthologs
    6
  • Human Ortholog
    RIN1, Ras and Rab interactor 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 9610
    neXtProt AC: NX_Q13671
    UniProt: Q13671

  • Chr Location
    11q13.2; chr11:66332063-66337235 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for disruptions in this gene display an enhanced conditioned response in cued conditioning protocols and avoidance learning tests.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024883 Ensembl Gene Model | MGI Sequence Detail 6591 C57BL/6J ±  kb
transcript ENSMUST00000025818 Ensembl | MGI Sequence Detail 4184 Not Applicable  
polypeptide ENSMUSP00000025818 Ensembl | MGI Sequence Detail 774 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 21
    cDNA 21

    Microarray probesets 4
References
more
  • Summaries
    All 32
    Gene Ontology 4
    Phenotypes 11
  • Earliest
    J:81922 Dhaka A, et al., The RAS effector RIN1 modulates the formation of aversive memories. J Neurosci. 2003 Feb 1;23(3):748-57
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory