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Mfsd7c
Gene Detail
 Symbol
Name
ID
Mfsd7c
major facilitator superfamily domain containing 7C
MGI:2384974
Synonyms CCT, Flvcr2, MGC:19050
Feature Type protein coding gene
Genetic Map
Chromosome 12
39.80 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr12:85746539-85813585 bp, + strand
From NCBI annotation of GRCm38

  67047 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9840  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken

Gene Tree: Mfsd7c

Human
homologs
Human Homolog FLVCR2, feline leukemia virus subgroup C cellular receptor family, member 2
NCBI Gene ID 55640
neXtProt AC  NX_Q9UPI3
Human Synonyms  C14orf58, CCT, EPV, FLVCRL14q, MFSD7C, PVHH
Human Chr (Location)  14q24.3; chr14:75578597-75648169 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human FLVCR2
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from APF )
Interactions
Mfsd7c interacts with 195 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process heme transport, transmembrane transport, ...
Component integral component of membrane, membrane, ...
Function heme binding, heme transporter activity
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (2)    Tissues (2)    Images (1)
Theiler Stages: 13
Assay TypeResults
RNA in situ 2
cDNA source data(31)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(31) cDNA(31)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000034258 (Evidence)
Entrez Gene217721 (Evidence)
UniGene301076
DFCITC1578505
DoTSDT.102555537
NIA Mouse Gene IndexU014214
Consensus CDS ProjectCCDS26062.1
International Mouse Knockout Project StatusMfsd7c
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 217721 NCBI Gene Model | MGI Sequence Detail 67047 C57BL/6J ±  kb
transcript NM_145447 RefSeq | MGI Sequence Detail 3435 C57BL/6 
polypeptide Q91X85 UniProt | EBI | MGI Sequence Detail 551 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(4) UniProt(3)
Polymorphisms SNPs within 2kb(274 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011701 Major facilitator superfamily
InterPro IPR020846 Major facilitator superfamily domain
InterPro IPR016196 Major facilitator superfamily domain, general substrate transporter
Protein Ontology PR:000007567 feline leukemia virus subgroup C receptor-related protein 2
Graphical View of Protein Domain Structure
References (Earliest) J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory