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Flvcr2 Gene Detail
Summary
  • Symbol
    Flvcr2
  • Name
    feline leukemia virus subgroup C cellular receptor 2
  • Synonyms
    CCT, Mfsd7c, MGC:19050
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384974
    NCBI Gene: 217721
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:85746539-85813585 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 39.80 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    274 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384974
protein coding gene Chr12:85746539-85813585 (.)
129S1/SvImJ MGP_129S1SvImJ_G0019964
protein coding gene Chr12:86546605-86620398 (+)
A/J MGP_AJ_G0019921
protein coding gene Chr12:83256261-83325323 (+)
AKR/J MGP_AKRJ_G0019897
protein coding gene Chr12:85509100-85578047 (+)
BALB/cJ MGP_BALBcJ_G0019901
protein coding gene Chr12:83595109-83663249 (+)
C3H/HeJ MGP_C3HHeJ_G0019707
protein coding gene Chr12:85990443-86062542 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020352
protein coding gene Chr12:89042531-89112780 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017970
protein coding gene Chr12:80146462-80216810 (+)
CAST/EiJ MGP_CASTEiJ_G0019257
protein coding gene Chr12:80975077-81045423 (+)
CBA/J MGP_CBAJ_G0019678
protein coding gene Chr12:92453862-92538220 (+)
DBA/2J MGP_DBA2J_G0019792
protein coding gene Chr12:82769100-82836908 (+)
FVB/NJ MGP_FVBNJ_G0019779
protein coding gene Chr12:81738378-81806805 (+)
LP/J MGP_LPJ_G0019866
protein coding gene Chr12:86424647-86496328 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019818
protein coding gene Chr12:95281625-95354081 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020385
protein coding gene Chr12:85123038-85193164 (+)
PWK/PhJ MGP_PWKPhJ_G0019020
protein coding gene Chr12:77285971-77354921 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018816
protein coding gene Chr12:79610001-79682344 (+)
WSB/EiJ MGP_WSBEiJ_G0019309
protein coding gene Chr12:85864785-85935545 (+)



Homology
more
  • Human Ortholog
    FLVCR2, feline leukemia virus subgroup C cellular receptor family member 2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    FLVCR2, feline leukemia virus subgroup C cellular receptor family member 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C14orf58, CCT, EPV, FLVCRL14q, MFSD7C, PVHH, SLC49A2
  • Links
    NCBI Gene ID: 55640
    neXtProt AC: NX_Q9UPI3
    UniProt: Q9UPI3

  • Chr Location
    14q24.3; chr14:75578597-75648169 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    15 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 217721 NCBI Gene Model | MGI Sequence Detail 67047 C57BL/6J ±  kb
    transcript NM_145447 RefSeq | MGI Sequence Detail 3435 C57BL/6  
    polypeptide Q91X85 UniProt | EBI | MGI Sequence Detail 551 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • InterPro Domains
      IPR011701 Major facilitator superfamily
      IPR020846 Major facilitator superfamily domain
      IPR036259 MFS transporter superfamily
    Molecular
    Reagents
    less
    • All nucleic 32
      cDNA 32

      Microarray probesets 3
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 2
      Gene Ontology 5
      Phenotypes 9
    • Earliest
      J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
    • Latest
      J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory