Automated description from the Alliance of Genome Resources (Release 7.1.0)
Predicted to enable heme binding activity and heme transmembrane transporter activity. Acts upstream of or within several processes, including brain development; endothelial tip cell fate specification; and in utero embryonic development. Predicted to be located in endoplasmic reticulum membrane and mitochondrial membrane. Predicted to be active in membrane. Is expressed in several structures, including central nervous system and yolk sac. Used to study proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome. Human ortholog(s) of this gene implicated in proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome. Orthologous to human FLVCR2 (FLVCR choline and putative heme transporter 2).