Flvcr2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Flvcr2
feline leukemia virus subgroup C cellular receptor 2
MGI:2384974

34 phenotypes from 3 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Flvcr2^tm1.1Tda/Flvcr2^tm1.1Tda Tg(Cdh5-cre/ERT2)1Rha/0 involves: C57BL/6J	abnormal vascular endothelial cell morphology	J:287134
	normal cardiovascular system phenotype	J:287134
	decreased endothelial cell proliferation	J:287134
Flvcr2^tm1.1Tda/Flvcr2^tm1.1Tda Tg(Tek-cre)5326Sato/0 involves: C57BL/6J	abnormal vascular development	J:287134
	preweaning lethality, complete penetrance	J:287134
Flvcr2^tm1.1Tda/Flvcr2^tm1.2Tda Tg(Cdh5-cre/ERT2)1Rha/0 involves: C57BL/6J	normal cardiovascular system phenotype	J:287134
Flvcr2^tm1.2Tda/Flvcr2^tm1.2Tda involves: C57BL/6J	abnormal brain vasculature morphology	J:287134
	abnormal pericyte morphology	J:287134
	abnormal vascular development	J:287134
	bradykinesia	J:287134
	brain inflammation	J:287134
	brain ischemia	J:287134
	brain vascular congestion	J:287134
	normal cardiovascular system phenotype	J:287134
	cyanosis	J:287134
	decreased angiogenesis	J:287134
	decreased endothelial cell proliferation	J:287134
	enlarged brain ventricles	J:287134
	hypoxia	J:287134
	neonatal lethality, complete penetrance	J:287134
Flvcr2^{tm1a(EUCOMM)Hmgu}/Flvcr2⁺ C57BL/6N-Flvcr2^{tm1a(EUCOMM)Hmgu}/Wtsi	increased circulating cholesterol level	J:211773
	increased circulating HDL cholesterol level	J:211773
	increased circulating LDL cholesterol level	J:211773
Flvcr2^{tm1a(EUCOMM)Hmgu}/Flvcr2^{tm1a(EUCOMM)Hmgu} C57BL/6N-Flvcr2^{tm1a(EUCOMM)Hmgu}/Wtsi	abnormal ductus venosus valve morphology	J:239583
	abnormal hypoglossal nerve topology	J:239583
	abnormal inferior vena cava morphology	J:239583
	abnormal lung morphology	J:239583
	abnormal Mullerian duct topology	J:239583
	abnormal vein morphology	J:239583
	abnormal Wolffian duct morphology	J:239583
	absent ductus venosus valve	J:239583
	absent segment of posterior cerebral artery	J:239583
	blood in lymph vessels	J:239583
	dual inferior vena cava	J:239583
	embryo tumor	J:239583
	hepatic portal vein stenosis	J:239583
	increased hemangioma incidence	J:239583
	preweaning lethality, complete penetrance	J:211773
	thin hypoglossal nerve	J:239583

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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