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Dennd3 Gene Detail
Summary
  • Symbol
    Dennd3
  • Name
    DENN/MADD domain containing 3
  • Synonyms
    E030003N15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2146009
    NCBI Gene: 105841
Location & Maps
more
  • Sequence Map
    Chr15:73512560-73572242 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      59683 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 34.01 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    DENND3, DENN domain containing 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DENND3, DENN domain containing 3
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 22898
    neXtProt AC: NX_A2RUS2

  • Chr Location
    8q24.3; chr8:141128621-141195804 (+)  GRCh38.p2

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    23 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    3
  • Radiation induced
    2
  • Targeted
    2
  • Genomic Mutations
    5 involving Dennd3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000032985 VEGA Gene Model | MGI Sequence Detail 59683 C57BL/6J ±  kb
transcript OTTMUST00000082263 VEGA | MGI Sequence Detail 5299 Not Applicable  
polypeptide OTTMUSP00000044077 VEGA | MGI Sequence Detail 1274 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    657 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 24

    Microarray probesets 3
References
more
  • Summaries
    All 24
    Diseases 1
    Gene Ontology 3
    Phenotypes 23
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:190275 Matsui T, et al., Small GTPase Rab12 regulates constitutive degradation of transferrin receptor. Traffic. 2011 Oct;12(10):1432-43

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/22/2016
MGI 6.04
The Jackson Laboratory