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Myocd
Gene Detail
Symbol

Name
ID
Myocd
myocardin
MGI:2137495
Synonyms
Srfcp
Feature Type
protein coding gene
Genetic Map
Chromosome 11
40.42 cM
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr11:65176561-65269941 bp, - strand
From VEGA annotation of GRCm38

  93381 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:17043  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: MKL/myocardin-like protein
Gene Tree: Myocd

Human
homologs
Human Homolog MYOCD, myocardin
NCBI Gene ID 93649
neXtProt AC  NX_Q8IZQ8
Human Synonyms  MYCD
Human Chr (Location)  17p11.2; chr17:12665890-12768949 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Targeted(7)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation exhibit embryonic lethality and fail to form vascular smooth muscle.
 
Human Diseases Modeled Using Mouse Myocd (1)    Alleles Annotated to Human Diseases(1)   
Interactions
Myocd interacts with 283 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (37 records)
Data Summary: Results (41)    Tissues (14)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 12
RT-PCR 29
cDNA source data(15)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(21) Genomic(1) cDNA(15) Primer pair(4) Other(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000005903 (Evidence)
Ensembl Gene ModelENSMUSG00000020542 (Evidence)
Entrez Gene214384 (Evidence)
UniGene32257
DFCITC1585239, TC1594864, TC1595366
DoTSDT.40179725, DT.94248872, DT.97356757
NIA Mouse Gene IndexU032924
Consensus CDS ProjectCCDS24843.1, CCDS48819.1
International Mouse Knockout Project StatusMyocd
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005903 VEGA Gene Model | MGI Sequence Detail 93381 C57BL/6J ±  kb
transcript OTTMUST00000013135 VEGA | MGI Sequence Detail 4935 Not Applicable 
polypeptide OTTMUSP00000006096 VEGA | MGI Sequence Detail 935 Not Applicable 

For the selected sequences
All sequences(51) RefSeq(9) UniProt(4)
Polymorphisms
SNPs within 2kb(865 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR004018 RPEL repeat
InterPro IPR003034 SAP domain
Protein Ontology PR:000010874 myocardin
References
(Earliest) J:70265 Wang D, et al., Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor. Cell. 2001 Jun 29;105(7):851-62
(Latest) J:210128 Weiss RM, et al., Brg1 determines urothelial cell fate during ureter development. J Am Soc Nephrol. 2013 Mar;24(4):618-26
All references(83)
Disease annotation references (1)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory