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Gpr45 Gene Detail
Summary
  • Symbol
    Gpr45
  • Name
    G protein-coupled receptor 45
  • Synonyms
    9230112G11Rik, PSP24alpha
  • Feature Type
    protein coding gene
  • IDs
    MGI:2135882
    NCBI Gene: 93690
  • Gene Overview
    MyGene.info: GPR45
Location & Maps
more
  • Sequence Map
    Chr1:42952872-43035456 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      82585 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 21.88 cM, cytoband C1
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    GPR45, G protein-coupled receptor 45
  • Vertebrate Orthologs
    8
  • Human Ortholog
    GPR45, G protein-coupled receptor 45
    Orthology source: HomoloGene
  • Synonyms
    PSP24, PSP24A, PSP24(ALPHA)
  • Links
    NCBI Gene ID: 11250
    neXtProt AC: NX_Q9Y5Y3

  • Chr Location
    2q11.1-q12; chr2:105241743-105243467 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Gpr45
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000045911 VEGA Gene Model | MGI Sequence Detail 82585 C57BL/6J ±  kb
transcript OTTMUST00000119941 VEGA | MGI Sequence Detail 3776 Not Applicable  
polypeptide OTTMUSP00000066543 VEGA | MGI Sequence Detail 373 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    205 from dbSNP Build 142
Protein
Information
less
  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000001645 G-protein coupled receptor 45
  • InterPro Domains
    IPR017452 GPCR, rhodopsin-like, 7TM
    IPR000276 G protein-coupled receptor, rhodopsin-like
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 4
Other
Accession IDs
less
MGI:1925334, MGI:2138544
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:68328 Kawasawa Y, et al., Brain-specific expression of novel G-protein-coupled receptors, with homologies to Xenopus PSP24 and human GPR45. Biochem Biophys Res Commun. 2000 Oct 5;276(3):952-6
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory