Sequence Detail

ID/Version

Q9EQQ4 (UniProt | EBI)

Last sequence update: 2001-03-01
Last annotation update: 2026-06-10

Sequence description from provider

RecName: Full=Protein carrier GPR45 {ECO:0000305};AltName: Full=G protein-coupled receptor 45 {ECO:0000303|PubMed:11027574};AltName: Full=PSP24-1 {ECO:0000303|PubMed:11027574};AltName: Full=PSP24-alpha {ECO:0000303|PubMed:11027574};

Provider

SWISS-PROT

Sequence

Polypeptide 373 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gpr45	G protein-coupled receptor 45	12	97	3	13

Sequence references in MGI

J:68328 Kawasawa Y, et al., Brain-specific expression of novel G-protein-coupled receptors, with homologies to Xenopus PSP24 and human GPR45. Biochem Biophys Res Commun. 2000 Oct 5;276(3):952-6
J:237251 Cui J, et al., Disruption of Gpr45 causes reduced hypothalamic POMC expression and obesity. J Clin Invest. 2016 Sep 01;126(9):3192-206
J:367505 Xun Y, et al., GPR45 modulates Galpha(s) at primary cilia of the paraventricular hypothalamus to control food intake. Science. 2025 Jun 5;388(6751):eadp3989
J:370121 Karolczak EO, et al., Uncovering the role of Gpr45 in obesity regulation. Mol Metab. 2025 May 29;98:102174