Csnk1a1
Gene Detail

Symbol Name ID

Csnk1a1 casein kinase 1, alpha 1 MGI:1934950

Synonyms

2610208K14Rik, 4632404G05Rik, 5430427P18Rik, CK1a

Feature Type

protein coding gene

Genetic Map

Chromosome 18

34.62 cM, cytoband D3
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr18:61555274-61590061 bp, + strand From VEGA annotation of GRCm38   34788 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:111694  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: kinase-related transforming protein
Gene Tree: Csnk1a1

Human homologs

Human Homolog		CSNK1A1, casein kinase 1, alpha 1
NCBI Gene ID		1452
neXtProt AC		NX_P48729
Human Synonyms		CK1, CK1a, CKIa, HLCDGP1, PRO2975
Human Chr (Location)		5q32; chr5:148874845-148931007 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(39) : Targeted(1) Gene trapped(38)

Gene Ontology (GO) classifications

All GO classifications: (31 annotations)

Process	cell cycle, cell division, ...
Component	centrosome, chromosome, ...
Function	ATP binding, glycoprotein binding, ...

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (62)    Tissues (49)    Images (3)
Theiler Stages: 23, 28

Assay Type	Results
RNA in situ	62

cDNA source data(30)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(32) cDNA(31) Primer pair(1)
Microarray probesets(8)

Other database links

VEGA Gene Model	OTTMUSG00000035876 (Evidence)
Ensembl Gene Model	ENSMUSG00000024576 (Evidence)
Entrez Gene	93687 (Evidence)
DFCI	TC1572012, TC1584994, TC1605869, TC1632500, TC1643294, TC1711046, TC1754013
DoTS	DT.101171666, DT.101283768, DT.101388473, DT.101388474, DT.110756546, DT.495165, DT.94377142, DT.94421618, DT.99865035
EC	2.7.11.1
Consensus CDS Project	CCDS37838.1
International Mouse Knockout Project Status	Csnk1a1

Sequences

Length	Strain/Species
genomic	OTTMUSG00000035876	VEGA Gene Model | MGI Sequence Detail	34788	C57BL/6J
transcript	OTTMUST00000091975	VEGA | MGI Sequence Detail	1860	Not Applicable
polypeptide	OTTMUSP00000050733	VEGA | MGI Sequence Detail	374	Not Applicable

All sequences(120) RefSeq(2) UniProt(11)

Polymorphisms

SNPs(127 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR017441	Protein kinase, ATP binding site
InterPro	IPR000719	Protein kinase, catalytic domain
InterPro	IPR011009	Protein kinase-like domain
InterPro	IPR008271	Serine/threonine-protein kinase, active site
Protein Ontology	PR:000005943	casein kinase I isoform alpha

References

(Earliest) J:46689 McInnes C, et al., Tissue-specific distribution of mouse casein kinase I alpha mRNA. DNA Seq. 1997;8(1-2):55-7
(Latest) J:174389 Sharma S, et al., Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex. Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11381-6
All references(44)

Other accession IDs

MGI:1914042, MGI:1915311, MGI:1926085