Csnk1a1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Csnk1a1
casein kinase 1, alpha 1
MGI:1934950

37 phenotypes from 3 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Tg(KRT14-cre/ERT)20Efu/0 involves: 129S1/Sv * 129X1/SvJ * CD-1	abnormal epidermal melanocyte morphology	J:253611
	abnormal epidermal pigmentation	J:253611
	abnormal epidermis stratum basale morphology	J:253611
	abnormal eumelanosome eumelanin content	J:253611
	abnormal skin physiology	J:253611
	decreased cellular sensitivity to ultraviolet irradiation	J:253611
	epidermal hyperplasia	J:253611
	hyperpigmentation	J:253611
	increased apoptosis	J:253611
	increased ear pigmentation	J:253611
	increased foot pigmentation	J:253611
	increased melanocyte number	J:253611
	increased tail pigmentation	J:253611
	normal neoplasm	J:253611
	thick epidermis	J:253611
Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Tg(Vil1-cre/ERT2)23Syr/0 involves: 129 * C57BL/6 * CD-1 * DBA/2	increased apoptosis	J:204886
	increased fibroblast apoptosis	J:204886
Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Tg(Vil1-cre/ERT2)23Syr/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2	abnormal jejunum crypts of Lieberkuhn morphology	J:291671
Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.2Ybn involves: 129 * BALB/c * C57BL/6 * CD-1	normal mortality/aging	J:204886
	normal neoplasm	J:204886
Csnk1a1^tm1.2Ybn/Csnk1a1^tm1.2Ybn involves: 129 * BALB/c * C57BL/6 * CD-1	embryonic lethality, complete penetrance	J:204886
Csnk1a1^{tm1c(KOMP)Wtsi}/Csnk1a1⁺ Tg(Mx1-cre)1Cgn/0 involves: C57BL/6 * C57BL/6N * CBA	abnormal erythroid lineage cell morphology	J:216977
	abnormal hematopoietic system morphology/development	J:216977
	abnormal megakaryocyte morphology	J:216977
	decreased bone marrow cell number	J:216977
	decreased common myeloid progenitor cell number	J:216977
	decreased hematopoietic stem cell number	J:216977
	decreased myeloid cell number	J:216977
	pancytopenia	J:216977
	premature death	J:216977
Csnk1a1^{tm1c(KOMP)Wtsi}/Csnk1a1^{tm1c(KOMP)Wtsi} Tg(Mx1-cre)1Cgn/0 involves: C57BL/6 * C57BL/6N * CBA	abnormal blood cell morphology	J:216977
	abnormal hematopoietic stem cell physiology	J:216977
	abnormal liver morphology	J:216977
	abnormal liver physiology	J:216977
	abnormal myocardium layer morphology	J:216977
	abnormal spleen red pulp morphology	J:216977
	bone marrow failure	J:216977
	cardiac ischemia	J:216977
	decreased hematopoietic stem cell number	J:216977
	extramedullary hematopoiesis	J:216977
	premature death	J:216977

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