Csnk1a1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Csnk1a1
casein kinase 1, alpha 1
MGI:1934950

12 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Cdkn1a^tm1Tyj/Cdkn1a^tm1Tyj Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Tg(Vil1-cre/ERT2)23Syr/0 involves: 129 * C57BL/6 * CD-1 * DBA/2	abnormal enterocyte proliferation	J:204886
	increased carcinoma incidence	J:204886
Crbn^tm1.1Ble/Crbn^tm1.1Ble Csnk1a1^tm1.1Ybn/Csnk1a1⁺ Tg(Mx1-cre)1Cgn/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA	increased physiological sensitivity to xenobiotic	J:267091
Csnk1a1^tm1.1Ybn/Csnk1a1⁺ Tg(Vil1-cre/ERT2)23Syr/0 Trp53^tm1Brn/Trp53^tm1Brn involves: 129 * C57BL/6 * CD-1 * DBA/2	increased carcinoma incidence	J:204886
Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Tg(Vil1-cre/ERT2)23Syr/0 Trp53^tm1Brn/Trp53^tm1Brn involves: 129 * C57BL/6 * CD-1 * DBA/2	abnormal enterocyte proliferation	J:204886
	increased apoptosis	J:204886
	increased carcinoma incidence	J:204886
	premature death	J:204886
Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Tg(Vil1-cre/ERT2)23Syr/0 Trp53^tm3.1Tyj/Trp53^tm3.1Tyj involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * DBA/2	abnormal enterocyte morphology	J:291671
	abnormal enterocyte proliferation	J:291671
Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Trp53^tm1Brn/Trp53^tm1Brn Tg(KRT14-cre/ERT)20Efu/0 involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * CD-1	abnormal epidermal layer morphology	J:253611
	abnormal epidermis stratum basale morphology	J:253611
	normal pigmentation phenotype	J:253611
Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Trp53^tm1Brn/Trp53^tm1Brn Tg(Vil1-cre/ERT2)23Syr/0 involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2	abnormal enterocyte morphology	J:291671
	abnormal enterocyte proliferation	J:291671
	abnormal intestine development	J:291671
	abnormal jejunum crypts of Lieberkuhn morphology	J:291671
Csnk1a1^tm1.1Ybn/Csnk1a1^tm1.1Ybn Trp53^tm2.1Tyj/Trp53^tm2.1Tyj Tg(Vil1-cre/ERT2)23Syr/0 involves: 129S1/Sv * 129X1/SvJ * 129S4/SvJae * C57BL/6 * DBA/2	abnormal enterocyte morphology	J:291671
	abnormal enterocyte proliferation	J:291671
	normal digestive/alimentary phenotype	J:291671

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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