Homozygous mutation of this gene results in premature death and increased incidence of tumor development. Reduced male fertility and testicular atrophy are also observed in mice with a hypomorphic allele.
|Process||apoptotic process, cellular response to transforming growth factor beta stimulus, ...|
|Component||cytoplasm, cytosol, ...|
|Function||2-hydroxytetrahydrofuran dehydrogenase activity, 3-hydroxymenthone dehydrogenase activity, ...|
|VEGA Gene Model||OTTMUSG00000030624 (Evidence)|
|Ensembl Gene Model||ENSMUSG00000004637 (Evidence)|
|Entrez Gene||80707 (Evidence)|
|DFCI||TC1613257, TC1576521, TC1592791|
|DoTS||DT.94161602, DT.94161601, DT.87038150, DT.60104019, DT.101722619|
|Consensus CDS Project||CCDS22691.1|
|International Mouse Phenotyping Consortium Status||Wwox|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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