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Zbtb20 Gene Detail
Summary
  • Symbol
    Zbtb20
  • Name
    zinc finger and BTB domain containing 20
  • Synonyms
    1300017A20Rik, 7330412A13Rik, A930017C21Rik, D16Wsu73e, HOF, Zfp288
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929213
    NCBI Gene: 56490
  • Gene Overview
    MyGene.info: ZBTB20
  • Alliance
  • Transcription Start Sites
    31 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:42875881-43642602 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 28.44 cM, cytoband B4
  • Mapping Data
    7 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3023 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929213
protein coding gene Chr16:42875817-43642602 (.)
129S1/SvImJ MGP_129S1SvImJ_G0022827
protein coding gene Chr16:41558567-42322927 (+)
A/J MGP_AJ_G0022792
protein coding gene Chr16:39659621-40415624 (+)
AKR/J MGP_AKRJ_G0022764
protein coding gene Chr16:40979442-41727056 (+)
BALB/cJ MGP_BALBcJ_G0022793
protein coding gene Chr16:39639572-40407918 (+)
C3H/HeJ MGP_C3HHeJ_G0022557
protein coding gene Chr16:41183401-41911212 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023240
protein coding gene Chr16:42523315-43303808 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020755
protein coding gene Chr16:39761693-40489242 (+)
CAST/EiJ MGP_CASTEiJ_G0022083
protein coding gene Chr16:41354769-42120792 (+)
CBA/J MGP_CBAJ_G0022528
protein coding gene Chr16:44337826-45143032 (+)
DBA/2J MGP_DBA2J_G0022660
protein coding gene Chr16:39405402-40141885 (+)
FVB/NJ MGP_FVBNJ_G0022635
protein coding gene Chr16:39397534-40130976 (+)
LP/J MGP_LPJ_G0022728
protein coding gene Chr16:41269644-42034229 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022654
protein coding gene Chr16:43714298-44542260 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023255
protein coding gene Chr16:40971710-41738191 (+)
PWK/PhJ MGP_PWKPhJ_G0021823
protein coding gene Chr16:39810022-40554405 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021654
protein coding gene Chr16:40897724-41640916 (+)
WSB/EiJ MGP_WSBEiJ_G0022127
protein coding gene Chr16:41077336-41845518 (+)



Homology
more
  • Human Ortholog
    ZBTB20, zinc finger and BTB domain containing 20
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ZBTB20, zinc finger and BTB domain containing 20
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DPZF, HOF, ODA-8S, PRIMS, ZNF288
  • Links
    NCBI Gene ID: 26137
    neXtProt AC: NX_Q9HC78
    UniProt: Q9HC78

  • Chr Location
    3q13.31; chr3:114314500-115147280 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9226
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: ZBTB20
  • Gene Tree
Human Diseases
less
  • Mutations/Alleles
    1 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    33 phenotypes from 3 alleles in 3 genetic backgrounds
    30 phenotypes from multigenic genotypes
    185 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit growth retardation, disrupted homeostasis, and premature death.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000022708 Ensembl Gene Model | MGI Sequence Detail 766722 C57BL/6J ±  kb
    transcript ENSMUST00000114694 Ensembl | MGI Sequence Detail 26901 Not Applicable  
    polypeptide ENSMUSP00000110342 Ensembl | MGI Sequence Detail 741 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 29
      cDNA 25
      Primer pair 3
      Other 1

      Microarray probesets 9
    Other
    Accession IDs
    less
    MGD-MRK-33985, MGI:106293, MGI:1915064, MGI:1925393, MGI:1925687, MGI:3057146
    References
    more
    • Summaries
      All 235
      Developmental Gene Expression 29
      Diseases 2
      Gene Ontology 8
      Phenotypes 185
    • Earliest
      J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
    • Latest
      J:265822 Chapman H, et al., Gsx transcription factors control neuronal versus glial specification in ventricular zone progenitors of the mouse lateral ganglionic eminence. Dev Biol. 2018 Oct 1;442(1):115-126

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
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    last database update
    11/13/2018
    MGI 6.13
    The Jackson Laboratory