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Zbtb20
Gene Detail
 Symbol
Name
ID
Zbtb20
zinc finger and BTB domain containing 20
MGI:1929213
Synonyms 1300017A20Rik, 7330412A13Rik, A930017C21Rik, D16Wsu73e, HOF, Zfp288
Feature Type protein coding gene
Genetic Map
Chromosome 16
28.44 cM, cytoband B4
Detailed Genetic Map ± 1 cM


Mapping data(7)
Sequence Map
Chr16:42875881-43642602 bp, + strand
From VEGA annotation of GRCm38

  766722 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9226  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Human
homologs
Human Homolog ZBTB20, zinc finger and BTB domain containing 20
NCBI Gene ID 26137
neXtProt AC  NX_Q9HC78
Human Synonyms  DPZF, HOF, ODA-8S, ZNF288
Human Chr (Location)  3q13.2; chr3:114314501-115147280 (-)  GRCh38
Alleles
and
phenotypes
All alleles(54) : Gene trapped(48) Targeted(6)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit growth retardation, disrupted homeostasis, and premature death.
 
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process negative regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-templated, ...
Component nucleus
Function DNA binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (17 records)
Data Summary: Results (265)    Tissues (169)    Images (35)
Theiler Stages: 2, 3, 4, 5, 11, 15, 17, 19, 21, 22, 23, 28
Assay TypeResults
RNA in situ 244
RT-PCR 21
cDNA source data(22)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress
Molecular
reagents
All nucleic(25) cDNA(22) Primer pair(3)
Microarray probesets(9)
Other database
links
VEGA Gene ModelOTTMUSG00000025618 (Evidence)
Ensembl Gene ModelENSMUSG00000036279 (Evidence), ENSMUSG00000022708 (Evidence)
Entrez Gene56490 (Evidence)
DFCITC1582715, TC1582802, TC1589935, TC1593361, TC1594971, TC1599611, TC1622202, TC1625808, TC1627885, TC1630677
DoTSDT.101367995, DT.110723206, DT.110723334, DT.40151985, DT.40182579, DT.55282211, DT.87068013, DT.87072363, DT.91327853, DT.91333288, DT.91338731, DT.94213228, DT.94213230, DT.97406802
NIA Mouse Gene IndexU017147, U046491, U046493, U046494, U144543, U176869, U340319
Consensus CDS ProjectCCDS28178.1, CCDS49851.1
International Mouse Knockout Project StatusZbtb20
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025618 VEGA Gene Model | MGI Sequence Detail 766722 C57BL/6J ±  kb
transcript OTTMUST00000062820 VEGA | MGI Sequence Detail 26901 Not Applicable 
polypeptide OTTMUSP00000031038 VEGA | MGI Sequence Detail 741 Not Applicable 

For the selected sequences
All sequences(195) RefSeq(54) UniProt(8)
Polymorphisms SNPs within 2kb(3044 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013069 BTB/POZ
InterPro IPR011333 BTB/POZ fold
InterPro IPR000210 BTB/POZ-like
InterPro IPR007087 Zinc finger, C2H2
InterPro IPR015880 Zinc finger, C2H2-like
InterPro IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain
Protein Ontology PR:000017568 zinc finger and BTB domain-containing protein 20
References (Earliest) J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
(Latest) J:199301 Lavado A, et al., Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013 Aug;140(16):3323-34
All references(59)
Other
accession IDs
MGD-MRK-33985, MGI:106293, MGI:1915064, MGI:1925393, MGI:1925687

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory