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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID
Zbtb20
zinc finger and BTB domain containing 20
MGI:1929213
32 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background
Annotated Term Reference
\Apoetm1Unc/\Apoetm2(APOE_i3)Yhg
\Zbtb20Tg(PDGFB-APPSwInd)20Lms/0
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2
amyloid beta deposits J:184138
\Apoetm1Unc/\Apoetm3(APOE_i4)Yhg
\Zbtb20Tg(PDGFB-APPSwInd)20Lms/0
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2
amyloid beta deposits J:184138
\C3tm1Crr/\C3tm1Crr
\Zbtb20Tg(PDGFB-APPSwInd)20Lms/?
involves: 129S4/SvJae * C57BL/6
amyloid beta deposits J:135902
increased microglial cell activation J:135902
loss of hippocampal neurons J:135902
\Gsaptm1.2Pggd/\Gsaptm1.2Pggd
\Zbtb20Tg(PDGFB-APPSwInd)20Lms/0
involves: C57BL/6 * C57BL/6J * C57BL/6N * DBA/2
normal behavior/neurological phenotype J:331150
normal homeostasis/metabolism phenotype J:331150
\Mapttm1Hnd/\Mapt+
\Zbtb20Tg(PDGFB-APPSwInd)20Lms/0
involves: 129X1/SvJ * C57BL/6 * DBA/2
abnormal neuron differentiation J:121330
abnormal neuron morphology J:121330
abnormal spatial learning J:121330
amyloid beta deposits J:121330
normal behavior/neurological phenotype J:121330
decreased susceptibility to pharmacologically induced seizures J:121330
\Mapttm1Hnd/\Mapttm1Hnd
\Zbtb20Tg(PDGFB-APPSwInd)20Lms/0
involves: 129X1/SvJ * C57BL/6 * DBA/2
abnormal neuron differentiation J:121330
abnormal neuron morphology J:121330
amyloid beta deposits J:121330
normal behavior/neurological phenotype J:121330
decreased susceptibility to pharmacologically induced seizures J:121330
\Pla2g4atm1Jvb/\Pla2g4a+
\Zbtb20Tg(PDGFB-APPSwInd)20Lms/0
involves: 129S4/SvJae * C57BL/6 * DBA/2
abnormal spatial learning J:141084
normal behavior/neurological phenotype J:141084
decreased anxiety-related response J:141084
normal mortality/aging J:141084
\Pla2g4atm1Jvb/\Pla2g4atm1Jvb
\Zbtb20Tg(PDGFB-APPSwInd)20Lms/0
involves: 129S4/SvJae * C57BL/6 * DBA/2
abnormal spatial learning J:141084
normal behavior/neurological phenotype J:141084
decreased anxiety-related response J:141084
normal mortality/aging J:141084
\Psen1tm4.1Shn/\Psen1+
\Zbtb20Tg(PDGFB-APPSwInd)20Lms/0
involves: 129 * C57BL/6 * C57BL/6J * DBA/2
amyloid beta deposits J:219929
\Tg(Camk2a-IDE)1Selk/0
\Zbtb20Tg(PDGFB-APPSwInd)20Lms/0
involves: C57BL/6 * DBA/2
abnormal neurite morphology J:87150
amyloid beta deposits J:87150
astrocytosis J:87150
gliosis J:87150
premature death J:87150
\Tg(Camk2a-MME)3Selk/0
\Zbtb20Tg(PDGFB-APPSwInd)20Lms/0
involves: C57BL/6 * DBA/2
abnormal neurite morphology J:87150
amyloid beta deposits J:87150
astrocytosis J:87150
gliosis J:87150
premature death J:87150
\Tg(Camk2a-tTA)1Mmay/0
\Zbtb20Tg(PDGFB-APPSwInd)20Lms/0
\Tg(tetO-MAPT)32Lms/0
involves: C57BL/6 * C57BL/6J * DBA/2
lethality, incomplete penetrance J:233816
premature death J:233816
\Tg(Camk2a-tTA)1Mmay/0
\Zbtb20Tg(PDGFB-APPSwInd)20Lms/0
\Tg(tetO-MAPT*A152T)L1Lms/0
involves: C57BL/6 * C57BL/6J * DBA/2
lethality at weaning J:233816
preweaning lethality, incomplete penetrance J:233816
\Tg(Gfap-TGFB1)64Lms/0
\Zbtb20Tg(PDGFB-APPSwInd)20Lms/0
involves: BALB/c * C57BL/6 * DBA/2 * SJL
abnormal blood vessel morphology J:167619
abnormal brain pia mater morphology J:167619
abnormal brain vasculature morphology J:167619
abnormal cholinergic neuron morphology J:167619
abnormal somatosensory cortex physiology J:167619
abnormal spatial learning J:167619
abnormal spatial reference memory J:167619
amyloid beta deposits J:167619
astrocytosis J:167619
cerebral amyloid angiopathy J:167619
decreased vasodilation J:167619
\Zbtb20Tg(PDGFB-APPSwInd)20Lms/0
B6.Cg-Zbtb20Tg(PDGFB-APPSwInd)20Lms
abnormal cerebral cortex pyramidal cell morphology J:118589
abnormal neurite morphology J:100954
amyloid beta deposits J:100954
impaired long-term object recognition memory J:331150
\Zbtb20Tg(PDGFB-APPSwInd)20Lms/0
involves: C57BL/6 * DBA/2
abnormal long-term object recognition memory J:121330
abnormal neuron differentiation J:121330
abnormal neuron morphology J:121330
abnormal spatial learning J:121330, J:141084
amyloid beta deposits J:62290, J:87150, J:121330
decreased anxiety-related response J:141084
hyperactivity J:121330, J:141084
increased susceptibility to pharmacologically induced seizures J:121330
neurodegeneration J:62290
premature death J:87150, J:121330, J:141084

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory