Automated description from the Alliance of Genome Resources (Release 5.3.0)
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Involved in several processes, including cellular response to glucose stimulus; positive regulation of glycolytic process; and regulation of gene expression. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Used to study Alzheimer's disease. Orthologous to human ZBTB20 (zinc finger and BTB domain containing 20).