Kcnq1ot1
Gene Detail

Symbol Name ID

Kcnq1ot1 KCNQ1 overlapping transcript 1 MGI:1926855

Synonyms

Kvlqt1-as, Lit1

Feature Type

unclassified non-coding RNA gene

Genetic Map

Chromosome 7

88.15 cM
Detailed Genetic Map ± 1 cM


Mapping data(8)

Sequence Map

Chr7:143213111-143296547 bp, - strand From NCBI annotation of GRCm38   83437 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Alleles and phenotypes

All alleles(15) : Targeted(9) Gene trapped(6)
 

Mice heterozygous for any of several independently generated targeted alleles exhibit abnormal imprinting and may display a growth deficiency.

 

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	gene silencing, hypermethylation of CpG island, ...
Function	chromatin binding, protein binding

External Resources: FuncBase

Expression

Literature Summary: (22 records)
Data Summary: Results (51)    Tissues (7)    Images (4)
Theiler Stages: 4, 15, 17, 25, 28

Assay Type	Results
RT-PCR	51

cDNA source data(18)
External Resources: Allen Institute   GEO  

Molecular reagents

All nucleic(28) Genomic(1) cDNA(19) Primer pair(8)
Microarray probesets(5)

Other database links

Entrez Gene	63830 (Evidence)
International Mouse Knockout Project Status	Kcnq1ot1

Sequences

Length	Strain/Species
genomic	63830	NCBI Gene Model | MGI Sequence Detail	83437	C57BL/6J
transcript	NR_001461	RefSeq | MGI Sequence Detail	83437	C57BL/6

All sequences(25) RefSeq(1)

Polymorphisms

PCR(1) : SNPs(0 from dbSNP Build 128)

References

(Earliest) J:10529 Bastian H, et al., A murine even-skipped homologue, Evx 1, is expressed during early embryogenesis and neurogenesis in a biphasic manner [published erratum appears in EMBO J 1991 Dec;10(12):3978]. EMBO J. 1990 Jun;9(6):1839-52
(Latest) J:190449 Korostowski L, et al., The Kcnq1ot1 long non-coding RNA affects chromatin conformation and expression of Kcnq1, but does not regulate its imprinting in the developing heart. PLoS Genet. 2012 Sep;8(9):e1002956
All references(49)