Kcnq1ot1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Kcnq1ot1
KCNQ1 overlapping transcript 1
MGI:1926855

15 phenotypes from 9 alleles in 8 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
\Kcnq1ot1^tm1.1Ckan/\Kcnq1ot1⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * M. spretus	abnormal DNA methylation	J:163857
	abnormal imprinting	J:163857
\Kcnq1ot1^tm1.1Ckan/\Kcnq1ot1^tm1.1Ckan involves: 129S1/Sv * 129X1/SvJ * C57BL/6	normal cellular phenotype	J:163857
	no abnormal phenotype detected	J:163857
\Kcnq1ot1^tm1.1Mjh/\Kcnq1ot1⁺ involves: 129S4/SvJae * C57BL/6J * FVB/N	decreased body weight	J:79882
	decreased embryo size	J:79882
	decreased kidney weight	J:79882
	decreased liver weight	J:79882
	decreased lung weight	J:79882
	maternal imprinting	J:79882
\Kcnq1ot1^tm1Tilg/\Kcnq1ot1⁺ involves: 129S1/Sv * C57BL/6 * M. spretus	abnormal imprinting	J:108700
	weight loss	J:108700
\Kcnq1ot1^tm2.1Ckan/\Kcnq1ot1⁺ \Meox2^tm1(cre)Sor/\Meox2⁺ involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * SD7	abnormal imprinting	J:185569
	decreased body weight	J:185569
	postnatal growth retardation	J:185569
\Kcnq1ot1^tm2.1Ckan/\Kcnq1ot1⁺ \Tg(CAG-cre/Esr1)5Amc/0 involves: 129S1/Sv 129X1/SvJ * C57BL/6 * CBA * SD7	abnormal DNA methylation	J:185569
	abnormal imprinting	J:185569
\Kcnq1ot1^tm2Mjh/\Kcnq1ot1⁺ involves: 129S4/SvJae * C57BL/6 * FVB/N	abnormal imprinting	J:130529
	decreased body size	J:130529
	decreased embryo size	J:130529
	small placenta	J:130529
\Kcnq1ot1^tm2Tilg/\Kcnq1ot1⁺ involves: 129S1/Sv * C57BL/6 * M. spretus	abnormal imprinting	J:108700
\Kcnq1ot1^tm2Tilg/\Kcnq1ot1⁺ involves: 129S1/Sv * M. spretus	abnormal imprinting	J:163857
\Kcnq1ot1^tm3Mjh/\Kcnq1ot1⁺ involves: 129S4/SvJae * C57BL/6 * FVB/N	genetic imprinting	J:130529
\Kcnq1ot1^tm3Tilg/\Kcnq1ot1⁺ involves: 129S1/Sv * C57BL/6 * M. spretus	abnormal imprinting	J:108700
\Kcnq1ot1^tm4Tilg/\Kcnq1ot1⁺ involves: 129S1/Sv * C57BL/6 * M. spretus	abnormal imprinting	J:108700

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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