Dpcd
Gene Detail

Symbol Name ID

Dpcd deleted in primary ciliary dyskinesia MGI:1924407

Synonyms

5330431N19Rik, Ndac

Feature Type

protein coding gene

Genetic Map

Chromosome 19

38.75 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr19:45560615-45578279 bp, + strand From Ensembl annotation of GRCm38   17665 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:9143  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Dpcd

Human homologs

Human Homolog		DPCD, deleted in primary ciliary dyskinesia homolog (mouse)
NCBI Gene ID		25911
neXtProt AC		NX_Q9BVM2
Human Chr (Location)		10q24.32; chr10:103348089-103369410 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(9) : Targeted(3) Gene trapped(6)
Human Diseases Modeled Using Mouse Dpcd (2)    Alleles Annotated to Human Diseases(2)   

Gene Ontology (GO) classifications

All GO classifications: (11 annotations)

Process	determination of left/right symmetry, epithelial cilium movement, ...
Component	cellular_component
Function	molecular_function

External Resources: FuncBase

Expression

cDNA source data(57)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(59) Genomic(2) cDNA(57)
Microarray probesets(2)

Other database links

Ensembl Gene Model	ENSMUSG00000041035 (Evidence)
Entrez Gene	226162 (Evidence)
UniGene	21978
DFCI	TC1579784, TC1587877, TC1614368
DoTS	DT.101392580, DT.101392581, DT.532464
NIA Mouse Gene Index	U019509
Consensus CDS Project	CCDS29862.1
International Mouse Knockout Project Status	Dpcd

Sequences

Length	Strain/Species
genomic	ENSMUSG00000041035	Ensembl Gene Model | MGI Sequence Detail	17665	C57BL/6J
transcript	ENSMUST00000047057	Ensembl | MGI Sequence Detail	1345	Not Applicable
polypeptide	ENSMUSP00000045683	Ensembl | MGI Sequence Detail	203	Not Applicable

All sequences(21) RefSeq(2) UniProt(1)

Polymorphisms

SNPs(94 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR026224	Protein DPCD
Protein Ontology	PR:000006644	protein DPCD

References

(Earliest) J:57316 Sidow A, et al., A novel member of the F-box/WD40 gene family, encoding dactylin, is disrupted in the mouse dactylaplasia mutant. Nat Genet. 1999 Sep;23(1):104-7
(Latest) J:185566 Vogel P, et al., Congenital hydrocephalus in genetically engineered mice. Vet Pathol. 2012 Jan;49(1):166-81
All references(32)

Other accession IDs

MGI:1345653