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Dpcd Gene Detail
Summary
  • Symbol
    Dpcd
  • Name
    deleted in primary ciliary dyskinesia
  • Synonyms
    5330431N19Rik, Ndac
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924407
    NCBI Gene: 226162
Location & Maps
more
  • Sequence Map
    Chr19:45560590-45578287 bp, + strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      17698 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 38.75 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    DPCD, deleted in primary ciliary dyskinesia homolog (mouse)
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DPCD, deleted in primary ciliary dyskinesia homolog (mouse)
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 25911
    neXtProt AC: NX_Q9BVM2

  • Chr Location
    10q24.32; chr10:101588332-101609653 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 9143
    1 human;1 mouse;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DPCD
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    13
  • Gene trapped
    6
  • Targeted
    7
  • Genomic Mutations
    5 involving Dpcd
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 226162 NCBI Gene Model | MGI Sequence Detail 17698 C57BL/6J ±  kb
transcript NM_172639 RefSeq | MGI Sequence Detail 1353 C57BL/6  
polypeptide Q8BPA8 UniProt | EBI | MGI Sequence Detail 203 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    98 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 59
    Genomic 2
    cDNA 57

    Microarray probesets 2
Other
Accession IDs
less
MGI:1345653
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:57316 Sidow A, et al., A novel member of the F-box/WD40 gene family, encoding dactylin, is disrupted in the mouse dactylaplasia mutant. Nat Genet. 1999 Sep;23(1):104-7
  • Latest
    J:196292 Marinic M, et al., An integrated holo-enhancer unit defines tissue and gene specificity of the Fgf8 regulatory landscape. Dev Cell. 2013 Mar 11;24(5):530-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory