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Tgds Gene Detail
Summary
  • Symbol
    Tgds
  • Name
    TDP-glucose 4,6-dehydratase
  • Synonyms
    2610017J16Rik, 2610025M23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923605
    NCBI Gene: 76355
Location & Maps
more
  • Sequence Map
    Chr14:118111911-118132765 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      20855 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 61.74 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    TGDS, TDP-glucose 4,6-dehydratase
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TGDS, TDP-glucose 4,6-dehydratase
    Orthology source: HGNC, HomoloGene
  • Synonyms
    CATMANS, SDR2E1, TDPGD
  • Links
    NCBI Gene ID: 23483
    neXtProt AC: NX_O95455

  • Chr Location
    13q32.1; chr13:94574054-94596275 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human TGDS associations

Human Disease Mouse Models
       Catel-Manzke Syndrome; CATMANS   OMIM: 616145
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (other)
    1
  • Gene trapped
    9
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Tgds
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 76355 NCBI Gene Model | MGI Sequence Detail 20855 C57BL/6J ±  kb
transcript NM_029578 RefSeq | MGI Sequence Detail 2265 C57BL/6  
polypeptide Q8VDR7 UniProt | EBI | MGI Sequence Detail 355 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    275 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 34
    cDNA 34

    Microarray probesets 3
Other
Accession IDs
less
MGI:1917161, MGI:2145686
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory