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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Tgds
TDP-glucose 4,6-dehydratase
MGI:1923605
47 phenotypes from 4 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Tgdsbub/Tgdsbub
C57BL/6J-Tgdsbub 		cleft palate J:263533
micrognathia J:263533
Tgdsem1(IMPC)Mbp/Tgds+
C57BL/6NCrl-Tgdsem1(IMPC)Mbp/Mmucd 		abnormal behavior J:211773
abnormal eye morphology J:211773
abnormal kidney morphology J:211773
abnormal placenta morphology J:211773
abnormal retina vasculature morphology J:211773
abnormal testis morphology J:211773
abnormal vitreous body morphology J:211773
cataract J:211773
decreased anxiety-related response J:211773
decreased locomotor activity J:211773
decreased thigmotaxis J:211773
enlarged testis J:211773
increased circulating alkaline phosphatase level J:211773
persistence of hyaloid vascular system J:211773
small kidney J:211773
Tgdsem1(IMPC)Mbp/Tgdsem1(IMPC)Mbp
C57BL/6NCrl-Tgdsem1(IMPC)Mbp/Mmucd 		abnormal chorioallantoic fusion J:374598
abnormal embryo morphology J:374598
abnormal embryo turning J:211773
abnormal forebrain morphology J:374598
abnormal head shape J:374598
abnormal heart looping J:211773, J:374598
abnormal heart morphology J:211773, J:374598
abnormal neural tube morphology J:211773
abnormal optic vesicle formation J:211773
abnormal pharyngeal arch morphology J:374598
abnormal placenta development J:374598
abnormal placenta labyrinth morphology J:374598
abnormal somite shape J:211773
abnormal trophoblast layer morphology J:374598
abnormal visceral yolk sac morphology J:374598
cardiac edema J:374598
embryonic growth retardation J:374598
embryonic lethality during organogenesis, complete penetrance J:374598
enlarged heart J:374598
incomplete embryo turning J:374598
pericardial edema J:374598
prenatal lethality prior to heart atrial septation J:211773
preweaning lethality, complete penetrance J:211773
Tgdsem1Ehm/Tgdsem2Ehm
involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCrl 		abnormal cranium size J:371720
abnormal metabolism J:371720
abnormal viscerocranium morphology J:371720
decreased length of long bones J:371720
short mandible J:371720
short nasal bone J:371720
shortened head J:371720
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory