Phenotype Images associated with this Gene

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Phenotype Images associated with this Gene

Symbol
Name
ID

Tgds
TDP-glucose 4,6-dehydratase
MGI:1923605

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Click on allele symbol for full phenotype details.

	Caption: Tgds^em1(IMPC)Mbp/Tgds^em1(IMPC)Mbp embryos have abnormal head shape, abnormal hearts accompanied by cardiac or pericardial edema, abnormal yolk sac morphology, and branchial arch defects and incomplete turning at E9.5. By E10.5, embryos are grossly abnormal. (details) Represented Alleles: Tgds^em1(IMPC)Mbp, TDP-glucose 4,6-dehydratase; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598
	Caption: Tgds^em1(IMPC)Mbp/Tgds^em1(IMPC)Mbp (-/-) placentas at E10.5 show an abnormal chorioallantoic interface (reduction in allantoic mesoderm) and multiple labyrinth zone defects. The labyrinth trophoblast layer is reduced and chorioallantoic branching is nearly absent. (details) Represented Alleles: Tgds^em1(IMPC)Mbp, TDP-glucose 4,6-dehydratase; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598
	Caption: E8.5 Tgds^em1(IMPC)Mbp/Tgds^em1(IMPC)Mbp (Tgds-/-) embryos have all 3 germ layers that appear appropriately patterned. (details) Represented Alleles: Tgds^em1(IMPC)Mbp, TDP-glucose 4,6-dehydratase; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598
	Caption: E9.5 Tgds^em1(IMPC)Mbp/Tgds^em1(IMPC)Mbp (Tgds -/- ) embryo has normal germ layer patterning but an abnormally large heart that is inappropriately looped. (details) Represented Alleles: Tgds^em1(IMPC)Mbp, TDP-glucose 4,6-dehydratase; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis Copyright: This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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