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Specc1l
Gene Detail
Symbol

Name
ID
Specc1l
sperm antigen with calponin homology and coiled-coil domains 1-like
MGI:1921642
Synonyms
4930470P14Rik, 4932439K10Rik, 9530057A13Rik, Cytsa, mKIAA0376, Specc1l
Feature Type
protein coding gene
Genetic Map
Chromosome 10
38.51 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr10:75212073-75312399 bp, + strand
From Ensembl annotation of GRCm38

  100327 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:15610  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Specc1l

Human
homologs
Human Homolog SPECC1L, sperm antigen with calponin homology and coiled-coil domains 1-like
NCBI Gene ID 23384
neXtProt AC  NX_Q69YQ0
Human Synonyms  CYTSA, OBLFC1
Human Chr (Location)  22q11.23; chr22:24270817-24417740 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human SPECC1L
Mutations,
alleles, and
phenotypes
All mutations/alleles(16) : Gene trapped(16)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Specc1l interacts with 289 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process actin cytoskeleton organization, cell adhesion, ...
Component actin cytoskeleton, cell junction, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (13)    Tissues (8)    Tissue x Stage Matrix (view)
Assay TypeResults
Immunohistochemistry 1
RNA in situ 12
cDNA source data(147)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(148) cDNA(147) Other(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000033444 (Evidence)
Entrez Gene74392 (Evidence)
UniGene27716
DFCITC1601200, TC1574755, TC1695301
DoTSDT.101737954, DT.101394479, DT.101342773, DT.492326, DT.91564400, DT.91359957
NIA Mouse Gene IndexU011656
Consensus CDS ProjectCCDS48598.1, CCDS48599.1
International Mouse Knockout Project StatusSpecc1l
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000033444 Ensembl Gene Model | MGI Sequence Detail 100327 C57BL/6J ±  kb
transcript ENSMUST00000040105 Ensembl | MGI Sequence Detail 5928 Not Applicable 
polypeptide ENSMUSP00000045099 Ensembl | MGI Sequence Detail 1135 Not Applicable 

For the selected sequences
All sequences(50) RefSeq(6) UniProt(9)
Polymorphisms
SNPs within 2kb(230 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001715 Calponin homology domain
Protein Ontology PR:000006159 cytospin-A
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:186807 Saadi I, et al., Deficiency of the cytoskeletal protein SPECC1L leads to oblique facial clefting. Am J Hum Genet. 2011 Jul 15;89(1):44-55
All references(32)
Other
accession IDs
MGI:1922253, MGI:2143573, MGI:2444709

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory