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Adgrg6
Gene Detail
Symbol

Name
ID
Adgrg6
adhesion G protein-coupled receptor G6
MGI:1916151
Synonyms
1190004A11Rik, DREG, Gpr126, LOC215798
Feature Type
protein coding gene
Genetic Map
Chromosome 10
5.43 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr10:14402585-14545036 bp, - strand
From Ensembl annotation of GRCm38

  142452 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10724  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

HCOP human homology predictions: ADGRG6
Protein SuperFamily: probable G protein-coupled receptor 126
Gene Tree: Adgrg6

Human
homologs
ADGRG6, adhesion G protein-coupled receptor G6
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 57211
neXtProt AC: NX_Q86SQ4

Human Synonyms: APG1, DREG, GPR126, PS1TP2, VIGR

Human Chr (Location): 6q24.1; chr6:142301919-142446266 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation die during organogenesis and display signs of circulatory failure.
 
Phenotype Images(5)
Interactions
Adgrg6 interacts with 327 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (5 records)
Data Summary: Results (33)    Tissues (20)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 8
Northern blot 1
RT-PCR 24
cDNA source data(29)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase LOC100489626 ; ZFIN adgrg6    NEW 
Molecular
reagents
All nucleic(31) cDNA(29) Primer pair(2)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000039116 (Evidence)
Entrez Gene 215798 (Evidence)
UniGene 440142
DFCI TC1598964, TC1586474
DoTS DT.487257
NIA Mouse Gene Index U031554
Consensus CDS Project CCDS35848.1
International Mouse Phenotyping Consortium Status Adgrg6
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039116 Ensembl Gene Model | MGI Sequence Detail 142452 C57BL/6J ±  kb
transcript ENSMUST00000041168 Ensembl | MGI Sequence Detail 6505 Not Applicable 
polypeptide ENSMUSP00000043055 Ensembl | MGI Sequence Detail 1165 Not Applicable 

For the selected sequences
All sequences(32) RefSeq(12) UniProt(2)
Polymorphisms
SNPs within 2kb(1549 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013320 Concanavalin A-like lectin/glucanase, subgroup
InterPro IPR000859 CUB domain
InterPro IPR001879 GPCR, family 2, extracellular hormone receptor domain
InterPro IPR017981 GPCR, family 2-like
InterPro IPR003910 GPCR, family 2, orphan receptor, GPR56
InterPro IPR000832 GPCR, family 2, secretin-like
InterPro IPR017983 GPCR, family 2, secretin-like, conserved site
InterPro IPR000203 GPS domain
Protein Ontology PR:000029514 G-protein coupled receptor 126
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:218304 Hamann J, et al., International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein-Coupled Receptors. Pharmacol Rev. 2015 Apr;67(2):338-67
All references(38)
Other
accession IDs
MGI:2143604, MGI:2143793, MGI:2685068

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory