Adgrg6^tm1Arte
Targeted Allele Detail

Summary

• Symbol: Adgrg6^tm1Arte
• Name: adhesion G protein-coupled receptor G6; targeted mutation 1, TaconicArtemis
• MGI ID: MGI:5819097
• Synonyms: Gpr126^fl
• Gene: Adgrg6 Location: Chr10:14278327-14421403 bp, - strand Genetic Position: Chr10, 5.43 cM
• Alliance: Adgrg6^tm1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:204175
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted 3 to exon 3 and a FRT-flanked neomycin selection cassette followed by a second loxP site was inserted 5 to exon 4. (J:147112)

Disease models

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adgrg6 Mutation: 63 strains or lines available

References

• Original: J:204175 Mogha A, et al., Gpr126 functions in Schwann cells to control differentiation and myelination via G-protein activation. J Neurosci. 2013 Nov 13;33(46):17976-85
• All: 9 reference(s)