Phenotypes Associated with This Genotype

Genotype
MGI:7266840

• Allelic Composition: Adgrg6^tm1Arte/Adgrg6^tm1Arte; Tg(Scx-GFP/cre)1Stzr/0
• Genetic Background: involves: 129S5/SvEvBrd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

abnormal tendon physiology ( J:313834 )

• mechanically weaker tail tendons with reduced elastic moduli

skeleton

abnormal tendon physiology ( J:313834 )

• mechanically weaker tail tendons with reduced elastic moduli

abnormal intervertebral disk morphology ( J:313834 )

• mildly wedged in the curved region in scoliotic mice at P120

abnormal nucleus pulposus morphology ( J:313834 )

• shifted in the curved region in scoliotic mice at P120

scoliosis ( J:313834 )

• at P120 with curve severity ranged between 12 and 30 degrees

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
idiopathic scoliosis		DOID:0060250		J:313834