About   Help   FAQ
Mto1
Gene Detail
Symbol

Name
ID
Mto1
mitochondrial translation optimization 1 homolog (S. cerevisiae)
MGI:1915541
Synonyms
2310039H01Rik, 5730419A02Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 9
43.65 cM, cytoband E1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:78448208-78475348 bp, + strand
From VEGA annotation of GRCm38

  27141 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:5876  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: GidA protein
Gene Tree: Mto1

Human
homologs
Human Homolog MTO1, mitochondrial tRNA translation optimization 1
NCBI Gene ID 25821
neXtProt AC  NX_Q9Y2Z2
Human Synonyms  COXPD10
Human Chr (Location)  6q13; chr6:73461731-73501456 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human MTO1
Mutations,
alleles, and
phenotypes
All mutations/alleles(21) : Gene trapped(18) Radiation induced(1) Targeted(2)
Genomic Mutations involving Mto1 (1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Mto1 interacts with 210 markers (Mir1a-1, Mir1a-2, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process mitochondrial tRNA wobble uridine modification, oxidation-reduction process, ...
Component mitochondrion
Function flavin adenine dinucleotide binding, poly(A) RNA binding
External Resources: FuncBase
Expression
cDNA source data(8)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(8) cDNA(8)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000019696 (Evidence)
Ensembl Gene ModelENSMUSG00000032342 (Evidence)
Entrez Gene68291 (Evidence)
DFCITC1593301, TC1577223
DoTSDT.94189517, DT.532558, DT.97341242
Consensus CDS ProjectCCDS23363.1
International Mouse Knockout Project StatusMto1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000019696 VEGA Gene Model | MGI Sequence Detail 27141 C57BL/6J ±  kb
transcript OTTMUST00000047154 VEGA | MGI Sequence Detail 2366 Not Applicable 
polypeptide OTTMUSP00000021296 VEGA | MGI Sequence Detail 669 Not Applicable 

For the selected sequences
All sequences(54) RefSeq(2) UniProt(7)
Polymorphisms
SNPs within 2kb(156 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013027 FAD-dependent pyridine nucleotide-disulphide oxidoreductase
InterPro IPR026904 GidA associated domain 3
InterPro IPR004416 Glucose-inhibited division protein A
InterPro IPR002218 Glucose-inhibited division protein A-related
InterPro IPR020595 Glucose-inhibited division protein A-related, conserved site
Protein Ontology PR:000010743 protein MTO1, mitochondrial
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(38)
Other
accession IDs
MGI:1917779

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/09/2014
MGI 5.20
The Jackson Laboratory