Mto1Gt(G019A03)Wrst
Gene trapped Allele Detail
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Symbol: |
Mto1Gt(G019A03)Wrst |
Name: |
mitochondrial tRNA translation optimization 1; gene trap G019A03, German Gene Trap Consortium |
MGI ID: |
MGI:4336382 |
Gene: |
Mto1 Location: Chr9:78355372-78381447 bp, + strand Genetic Position: Chr9, 43.65 cM, cytoband E1
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Alliance: |
Mto1Gt(G019A03)Wrst page
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Mutant Cell Line: |
G019A03 |
Germline Transmission: |
Earliest citation of germline transmission:
J:223246
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Parent Cell Line: |
TBV2 (ES Cell)
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Strain of Origin: |
129S2/SvPas
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Allele Type: |
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Gene trapped (Hypomorph) |
Mutation: |
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Insertion of gene trap vector
Vector: U3CEO
Vector Type: secretory trap
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Mutation details: Trapped gene association determined by genome coordinate overlap and strand. The gene trap vector U3CEO inserted into intron 6 of Mto1. Quantitative RT-PCR analysis of mRNA levels in heart from homozygotes indicate a 63% reduction compared to controls, indicating this is a hypomorphic allele.
(J:223246)
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Sequence Tags: |
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Sequence tag details (1 tag)
Tag ID |
GenBank ID |
Method |
Tag Location (trapped strand)* |
Select |
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Genome Context: |
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Genome Browser view of this mutation
14 gene trap insertions have trapped this gene
View all gene trap sequence tags in this region
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Mto1 Mutation: |
37 strains or lines available
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Original: |
J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008; |
All: |
4 reference(s) |
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