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Tubb4b Gene Detail
Summary
  • Symbol
    Tubb4b
  • Name
    tubulin, beta 4B class IVB
  • Synonyms
    4930542G03Rik, MGC:28623, MGC:6713, Tubb2c
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915472
    NCBI Gene: 227613
  • Gene Overview
    MyGene.info: TUBB4B
Location & Maps
more
  • Sequence Map
    Chr2:25222160-25224702 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2543 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 17.08 cM, cytoband A3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    TUBB4B, tubulin beta 4B class IVb
  • Vertebrate Orthologs
    11
  • Human Ortholog
    TUBB4B, tubulin beta 4B class IVb
    Orthology source: HGNC, HomoloGene
  • Synonyms
    Beta2, TUBB2, TUBB2C
  • Links
    NCBI Gene ID: 10383
    neXtProt AC: NX_P68371

  • Chr Location
    9q34; chr9:137241259-137243707 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    19
  • Gene trapped
    16
  • Targeted
    3
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011806 VEGA Gene Model | MGI Sequence Detail 2543 C57BL/6J ±  kb
transcript OTTMUST00000027720 VEGA | MGI Sequence Detail 1598 Not Applicable  
polypeptide OTTMUSP00000012597 VEGA | MGI Sequence Detail 445 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    6 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 7
References
more
  • Summaries
    All 38
    Developmental Gene Expression 6
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:35227 Wang D, et al., The mammalian beta-tubulin repertoire: hematopoietic expression of a novel, heterologous beta-tubulin isotype. J Cell Biol. 1986 Nov;103(5):1903-10
  • Latest
    J:233746 Wang X, et al., Expression of histone deacetylase 3 instructs alveolar type I cell differentiation by regulating a Wnt signaling niche in the lung. Dev Biol. 2016 Jun 15;414(2):161-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory