Phenotypes Associated with This Genotype

Genotype
MGI:8328256

• Allelic Composition: Tubb4b^em1Golab/Tubb4b⁺
• Genetic Background: C57BL/6J-Tubb4b^em1Golab

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

abnormal spermatogenesis ( J:360308 )

♂

male infertility ( J:360308 )

♂

respiratory system

abnormal respiratory motile cilium morphology ( J:360308 )

• 20% reduction in airway cilia length

cellular

abnormal respiratory motile cilium morphology ( J:360308 )

• 20% reduction in airway cilia length

vision/eye

vision/eye phenotype ( J:360308 )

N • mice do not develop retinal degeneration, even when aged

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
NOT	Leber congenital amaurosis with early-onset deafness	DOID:0112240	OMIM:617879	J:360308